ID A0A1H9CXQ5_9FLAO Unreviewed; 317 AA.
AC A0A1H9CXQ5;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE SubName: Full=D-3-phosphoglycerate dehydrogenase {ECO:0000313|EMBL:SEQ06002.1};
GN ORFNames=SAMN05444005_105148 {ECO:0000313|EMBL:SEQ06002.1};
OS Flavobacterium urocaniciphilum.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Flavobacterium.
OX NCBI_TaxID=1299341 {ECO:0000313|EMBL:SEQ06002.1, ECO:0000313|Proteomes:UP000198648};
RN [1] {ECO:0000313|EMBL:SEQ06002.1, ECO:0000313|Proteomes:UP000198648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 27078 {ECO:0000313|EMBL:SEQ06002.1,
RC ECO:0000313|Proteomes:UP000198648};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the D-isomer specific 2-hydroxyacid
CC dehydrogenase family. {ECO:0000256|RuleBase:RU003719}.
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DR EMBL; FOEI01000005; SEQ06002.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H9CXQ5; -.
DR STRING; 1299341.SAMN05444005_105148; -.
DR OrthoDB; 9805416at2; -.
DR Proteomes; UP000198648; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd05303; PGDH_2; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR006139; D-isomer_2_OHA_DH_cat_dom.
DR InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43761:SF1; 2-HACID_DH DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR43761; D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_1G13630); 1.
DR Pfam; PF00389; 2-Hacid_dh; 1.
DR Pfam; PF02826; 2-Hacid_dh_C; 1.
DR SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|RuleBase:RU003719};
KW Reference proteome {ECO:0000313|Proteomes:UP000198648}.
FT DOMAIN 6..317
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase
FT catalytic"
FT /evidence="ECO:0000259|Pfam:PF00389"
FT DOMAIN 107..293
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02826"
SQ SEQUENCE 317 AA; 34347 MW; 66CEA3FA8F802B60 CRC64;
MKILANDGIS KSGIKALEKA GFEVITTKVA QEQVANYINT NNVQVVLVRS ATKIKQDIID
ACPGLKIIGR GGVGMDNIDV DYARSKGIHV INTPAASSES VAELVFAHLF SGVRFLHDAN
RNMPLEGDTN FNGLKKAYAN GLELRGKTLG IIGFGRIGQA VAKMALGLGM KVIAVDKYVN
EAVVRVDFYN GQFINVEIVT ESMEDLFKHS DFITLHVPAQ EGYVIDKAEF DLMKDEVGIV
NCSRGGVINE VALVEALDAE KVLFAGLDVF ENEPTPEIQI LMHPKISLTP HIGAATLEAQ
DRIGTELAEQ IISLLKN
//
