ID A0A1H9CY72_9FLAO Unreviewed; 943 AA.
AC A0A1H9CY72;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=UvrABC system protein A {ECO:0000256|ARBA:ARBA00039316};
DE AltName: Full=Excinuclease ABC subunit A {ECO:0000256|ARBA:ARBA00042156};
GN ORFNames=SAMN05444005_105152 {ECO:0000313|EMBL:SEQ06091.1};
OS Flavobacterium urocaniciphilum.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Flavobacterium.
OX NCBI_TaxID=1299341 {ECO:0000313|EMBL:SEQ06091.1, ECO:0000313|Proteomes:UP000198648};
RN [1] {ECO:0000313|EMBL:SEQ06091.1, ECO:0000313|Proteomes:UP000198648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 27078 {ECO:0000313|EMBL:SEQ06091.1,
RC ECO:0000313|Proteomes:UP000198648};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. UvrA family.
CC {ECO:0000256|ARBA:ARBA00038000}.
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DR EMBL; FOEI01000005; SEQ06091.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H9CY72; -.
DR STRING; 1299341.SAMN05444005_105152; -.
DR OrthoDB; 9809851at2; -.
DR Proteomes; UP000198648; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR CDD; cd03271; ABC_UvrA_II; 1.
DR Gene3D; 1.10.8.280; ABC transporter ATPase domain-like; 1.
DR Gene3D; 1.20.1580.10; ABC transporter ATPase like domain; 2.
DR Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR013815; ATP_grasp_subdomain_1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004602; UvrA.
DR InterPro; IPR041552; UvrA_DNA-bd.
DR InterPro; IPR041102; UvrA_inter.
DR NCBIfam; TIGR00630; uvra; 1.
DR PANTHER; PTHR43152; UVRABC SYSTEM PROTEIN A; 1.
DR PANTHER; PTHR43152:SF3; UVRABC SYSTEM PROTEIN A; 1.
DR Pfam; PF17755; UvrA_DNA-bind; 1.
DR Pfam; PF17760; UvrA_inter; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA excision {ECO:0000256|ARBA:ARBA00022769};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Excision nuclease {ECO:0000256|ARBA:ARBA00022881};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000198648};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 607..939
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 943 AA; 105796 MW; 043CB0EB77573CF6 CRC64;
MQHSEETIEI IGARAHNLKN IDVTIPREKL VVITGLSGSG KSSLAFDTIY AEGQRRYIET
FSAYARQFLG GLERPDVDKI DGLSPVIAIE QKTTNKSPRS TVGTITEIYD FLRLLYARAS
DAYSYNTGEK MVSYSDDQIK ELILEEFDGK RINILAPVIR SRKGHYRELF EQIAKQGFLK
VRIDGVIKDL EYGMKVDRYK THDIEIVIDR IAVKNDEDTD KRLTESIKVA MHHGDDIMMV
IEQDTEEPRF YSRSLMCPTS GISYPNPEPN NFSFNSPKGA CPTCNGLGVV NEINLQKIIP
NPKVSIKSGG FAPLGEYKSS WIFKQLEFIG EKFGFKLTDP IEAIPAEAME MILYGGNEKF
SVVSKVMGIT KDYKIDFEGI SNFIKNQFEQ SETQSIRRWA KEFMDENNCS ECEGTRLRKE
VLYFKINDKS IGDLVHMDIV ELSKWFSELP QHLSDKQQTI AAEILKEINA RINFLLDVGL
DYLCLNRSSK TLSGGEAQRI RLATQIGSQL VGVLYILDEP SIGLHQRDNE RLIKSLESLR
DIGNSVLVVE HDKDMIVRAD HVIDIGPKAG KHGGQIISQG TPAELLKEKT ITAQFLNGKM
QIEVPKTRRE GNGKFLKLKG ATGNNLKNVS IDIPLGKMIC VSGVSGSGKS TLINETLYPI
LNAHFYNAVK KPQPYKKIEG LEHIDKVIDI DQSPIGRTPR SNPATYTDVF SEIRTLFTMT
PESMIRGYKP GRFSFNVKGG RCETCEGSGV RTIEMSFLPD VYVECETCQG KRFNRETLEI
RYKGKSISDV LNMTVDEAVE FFENIPKIYR KVKTIQDVGL GYITLGQQST TLSGGEAQRI
KLAGELSKKD TGNTFYILDE PTTGLHFEDI RILMDVINKL VDKGNTVLII EHNLDVIKLA
DYIIDIGLEG GKGGGEVLCT GTPEEIVKNK KSYTAQFLKK ELS
//
