ID   A0A1H9D315_9LACT        Unreviewed;       467 AA.
AC   A0A1H9D315;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Arginine:ornithine antiporter, APA family {ECO:0000313|EMBL:SEQ07880.1};
GN   ORFNames=SAMN04488558_10511 {ECO:0000313|EMBL:SEQ07880.1};
OS   Ignavigranum ruoffiae.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Aerococcaceae; Ignavigranum.
OX   NCBI_TaxID=89093 {ECO:0000313|EMBL:SEQ07880.1, ECO:0000313|Proteomes:UP000198833};
RN   [1] {ECO:0000313|EMBL:SEQ07880.1, ECO:0000313|Proteomes:UP000198833}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 15695 {ECO:0000313|EMBL:SEQ07880.1,
RC   ECO:0000313|Proteomes:UP000198833};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the amino acid-polyamine-organocation (APC)
CC       superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2)
CC       family. {ECO:0000256|ARBA:ARBA00008220}.
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DR   EMBL; FOEN01000005; SEQ07880.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H9D315; -.
DR   STRING; 89093.SAMN04488558_10511; -.
DR   OrthoDB; 9762947at2; -.
DR   Proteomes; UP000198833; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006865; P:amino acid transport; IEA:InterPro.
DR   Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR   InterPro; IPR002293; AA/rel_permease1.
DR   InterPro; IPR004754; Amino_acid_antiprt.
DR   NCBIfam; TIGR00905; 2A0302; 1.
DR   PANTHER; PTHR42770; AMINO ACID TRANSPORTER-RELATED; 1.
DR   PANTHER; PTHR42770:SF4; ARGININE_ORNITHINE ANTIPORTER-RELATED; 1.
DR   Pfam; PF13520; AA_permease_2; 1.
DR   PIRSF; PIRSF006060; AA_transporter; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198833};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        7..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        35..58
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        102..119
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        125..142
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        154..175
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        204..222
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        234..257
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        277..299
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        335..356
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        362..382
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        394..411
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        417..435
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        447..464
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   467 AA;  51833 MW;  DB352A5F2FE65B9F CRC64;
     MNQDNKMGFW SLMGLIITTI IGSGIFNLSK EMASVASQAG VMIGWLITGV GMGCLALAMQ
     EVSRRRPDLE SGIFNYARAG FGEYIGFNSA WGYWISSLIK NAAYGTLIFS ALSYFFPYFE
     DGQNLYSFLG ASLLLWLIHG LISRGVRQAE LVNAIILLAK LAPIIVFLIL ALTAFRFDLF
     QVDFWGQLDQ NIQLGSLSQQ VKETMLVSVF SFIGLESAVA FSGKAQDQRQ VGTATVLAFC
     SVTLIYAAVT ILSFGILSRE EIVQLPNPSL AYLMEALIGR PGAIFVNIGV IFSIFGAWFS
     STLLNEEVVY QAAHLGLFPA YFDQRNQRLI SMRSLTVSNG LIQLLFLSFL LIPNAYSNLT
     KLSSASILFS YTCMALYLVK LNAKQTEASS QTKTSSLIAW VASIYMIWLI YASGRTYLIL
     SVLLLFPGSL LYMGLQWQKG RKVFKNYEWI IFIILLLGFC YSLAQLI
//