ID   A0A1H9DG06_9FIRM        Unreviewed;      1326 AA.
AC   A0A1H9DG06;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Prepilin-type N-terminal cleavage/methylation domain-containing protein {ECO:0000313|EMBL:SEQ11713.1};
GN   ORFNames=SAMN02910369_01238 {ECO:0000313|EMBL:SEQ11713.1};
OS   Lachnospiraceae bacterium NE2001.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=1520823 {ECO:0000313|EMBL:SEQ11713.1, ECO:0000313|Proteomes:UP000199680};
RN   [1] {ECO:0000313|EMBL:SEQ11713.1, ECO:0000313|Proteomes:UP000199680}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NE2001 {ECO:0000313|EMBL:SEQ11713.1,
RC   ECO:0000313|Proteomes:UP000199680};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FOEK01000007; SEQ11713.1; -; Genomic_DNA.
DR   STRING; 1520823.SAMN02910369_01238; -.
DR   OrthoDB; 2000191at2; -.
DR   Proteomes; UP000199680; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.700.10; Glycoprotein, Type 4 Pilin; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR   InterPro; IPR005046; DUF285.
DR   InterPro; IPR011889; Liste_lipo_26.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR012902; N_methyl_site.
DR   InterPro; IPR045584; Pilin-like.
DR   NCBIfam; TIGR02532; IV_pilin_GFxxxE; 1.
DR   NCBIfam; TIGR02167; Liste_lipo_26; 3.
DR   Pfam; PF03382; DUF285; 2.
DR   Pfam; PF07963; N_methyl; 1.
DR   SUPFAM; SSF52058; L domain-like; 1.
DR   SUPFAM; SSF54523; Pili subunits; 1.
DR   PROSITE; PS00409; PROKAR_NTER_METHYL; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199680};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        47..69
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          235..260
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        235..249
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1326 AA;  147158 MW;  EF5BBCA4AEE9F7D3 CRC64;
     MISRKALGMV WKVFGLEHDY AGLGESSVNR IKKCSSSQKN SEKGFTLVEL IVVLVILAIL
     AAAVVPGLLG FTDHANKKKH ISEAKEALSA TESMLSDAYT EGLVYLPRRV REEAFNTSGL
     KASTEFTINT VKNFKNADGT YNSVASYTVA SALFKADDGI YVYYNGSEWR VLDEELTADK
     DIIAGKTGVK TGENDNYIVV WPWDSEKAVK DSASSSNNIA KNEDEGIDTY IDEEDEETRI
     EETESADGEE VIDEPSRPGM NYNTVTLTLL GAVDTDKTNV KLINNERTNR TVVKFGNKTA
     FTTTFTADGS ENGTLSDTPN PVVQDKDNLD ETSLKWVKSD DSNVIYSSIS EIKTYLNENA
     AVPGFDSVTF VAEVKEKSIE DIPVSFFAYN NGTQSVEVSG GKKDSDNDGV FDTIEAKYGI
     ISHAVVCDVD LSNVNVTQAD IDGNDVSGTP KPNEGAITFD NNWVIKDTNE STTGGSIICI
     KDENDEIIKA NSENISEVIS NRISALVDTD GDGAIDKDEN NIPVVKNEGI VFLAPADINK
     TLHVRGIINS GNYAGLVSFD DTETVAAEND FSIEESYVKY ELDGKIYKDN SKTSPLVFNG
     EGAYSVFDDN KLVFSNKKLK VKWWNLYKCD KNLTEEALKN ETDMTSDGRT REKDIKNVSG
     NTIDANLSEL LIKDKLFGNN EYGELAVVDV APQTTLLKHD VKGKQSPVRK LIRDVANGKI
     DYITSINYIP FSIVEKNTTN IFMERCLSTT TVRQQTGENA RLLCRDEEGN YLVNDSDRDE
     KYPAYTVAYS IRKPNNDPQT QSDSAYLYDV YIVTEDDSEI KVQDSCKEMF SNCQRMTVNT
     MVAKLETTDV TDMSYMFYKC CSITKFDLSN FNTSKVTDMS YLFDNCRSAA SINVSSFDTS
     KVVTMRNMFG NSMIDKQPMY NNVLTKLDLS NFSTQSLLKD ASKTRDSNNG IRDMFIRCSA
     LQTIIVDPTQ WRVDKFVYMD GNQASDSASG GNTFKGCVSL KGGAGTTPEI VRDVYNDGDI
     NVDQRTFSMT SKYAVADEYP EENYNGDDTA AGEHGYFTAM KAASLVQLND NWVYNKLGVQ
     KTSITGFSRE TTLTREDVLA IDDKISLSTT DSEVPVYMWV NENNELKWWS QATTISLNSN
     ATKMFNGWTS LKSIDLTDFD LSQVTDFSEM FNGCTSLTSA RLVIDTSETS NVKMTSMFKG
     TAVKTVSITG DWSNVTDISY MFSDAHSIQD IDFGERADMS NLQTIAFMFF NLNKSNVDTK
     FNAFAHAASS WDMGDNPLFN TPELYDNSSE KIKITNNLGW GGKTFTDYNG NQYKIMNNKY
     VQLQTP
//