ID   A0A1H9DII1_9GAMM        Unreviewed;       966 AA.
AC   A0A1H9DII1;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Sarcosine oxidase subunit alpha {ECO:0000313|EMBL:SEQ13285.1};
GN   ORFNames=SAMN03080615_00572 {ECO:0000313|EMBL:SEQ13285.1};
OS   Amphritea atlantica.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC   Oceanospirillaceae; Amphritea.
OX   NCBI_TaxID=355243 {ECO:0000313|EMBL:SEQ13285.1, ECO:0000313|Proteomes:UP000198749};
RN   [1] {ECO:0000313|Proteomes:UP000198749}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 18887 {ECO:0000313|Proteomes:UP000198749};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the GcvT family.
CC       {ECO:0000256|ARBA:ARBA00008609}.
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DR   EMBL; FOGB01000001; SEQ13285.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H9DII1; -.
DR   STRING; 355243.SAMN03080615_00572; -.
DR   OrthoDB; 5287468at2; -.
DR   Proteomes; UP000198749; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.10.20.440; 2Fe-2S iron-sulphur cluster binding domain, sarcosine oxidase, alpha subunit, N-terminal domain; 1.
DR   Gene3D; 1.10.10.1100; BFD-like [2Fe-2S]-binding domain; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR042204; 2Fe-2S-bd_N.
DR   InterPro; IPR041854; BFD-like_2Fe2S-bd_dom_sf.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR023753; FAD/NAD-binding_dom.
DR   InterPro; IPR028896; GCST/YgfZ/DmdA.
DR   InterPro; IPR013977; GCV_T_C.
DR   InterPro; IPR006222; GCV_T_N.
DR   InterPro; IPR029043; GcvT/YgfZ_C.
DR   InterPro; IPR041117; SoxA_A3.
DR   InterPro; IPR027266; TrmE/GcvT_dom1.
DR   PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR   PANTHER; PTHR43757:SF2; AMINOMETHYLTRANSFERASE, MITOCHONDRIAL; 1.
DR   Pfam; PF13510; Fer2_4; 1.
DR   Pfam; PF01571; GCV_T; 1.
DR   Pfam; PF08669; GCV_T_C; 1.
DR   Pfam; PF07992; Pyr_redox_2; 1.
DR   Pfam; PF17806; SO_alpha_A3; 1.
DR   PRINTS; PR00368; FADPNR.
DR   PRINTS; PR00469; PNDRDTASEII.
DR   SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   SUPFAM; SSF103025; Folate-binding domain; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT   DOMAIN          168..422
FT                   /note="FAD/NAD(P)-binding"
FT                   /evidence="ECO:0000259|Pfam:PF07992"
FT   DOMAIN          497..581
FT                   /note="SoxA A3"
FT                   /evidence="ECO:0000259|Pfam:PF17806"
FT   DOMAIN          592..855
FT                   /note="Aminomethyltransferase folate-binding"
FT                   /evidence="ECO:0000259|Pfam:PF01571"
FT   DOMAIN          879..958
FT                   /note="Glycine cleavage T-protein C-terminal barrel"
FT                   /evidence="ECO:0000259|Pfam:PF08669"
SQ   SEQUENCE   966 AA;  106810 MW;  1BF0DF7DB8B726B6 CRC64;
     MSSEKRLKAP MGLLIDREKP LSFSFEGKQY RGFAGDSIAS ALLANQQWLM SRSFKYHRPR
     APLTMAGQDA NTLVQLGGEP NVLADREMIR EGISAEGQNY NGTLEGDKDA YLGHFGRFMP
     VGFYYRSFFK PMGVWDKWES FIRDKAGLGK LDLTFKPEYY DKKYLFTDVV VIGSGPAGLS
     AALKAADAGA KVLLVEEMPL LGGALTYNRF DIAGQQADSL RCELIDKVTA HDNIEVMTDT
     VCNAWVTDNY LPLIRGKRFY KLRAKECIVA SGAYEQHVVF RNNDLPGIML CSAVTRLMKL
     YAVRPGSRAV VLTGNDDGYL TALELLENGV EVAAIVDLRS EHPWPELLGA VKQKGVQVIQ
     NSTVYEALPS KGNKHIRGVD IRTIVGEGEV SEFSTTLECD LLCMSAGYMP AYQLLCQAGA
     QLSYNDDAAE FTLSGLPQGV HIAGSVNGLH TLEAVLNDGA NAAIRALRRL QLSDESEQPV
     SCLAKPNFSW PIFSHPKGKD FVDYDEDLQA KDIVNATRLG YRDVQLVKRF STVGMGPSQG
     RHSALPTARL VAKSTERTVT QTGVTTARPP FAPEKLAHVA GRIFDPRRHT AMHHRHLELG
     AKMIPAGNWR RPAFYGDAAQ RDRWIREEAE HVRSRVGLID VSTLGGIEIR GADAAEFMNR
     IYTFAFLKQP VGKTRYAVLT NEHGVVIDDG VACRISEDHF YVTATTSGVE RVYRDMTKWN
     AQWRLDVDIL HVTSAFAAVN LAGPDARKVL QQLVDDVDLS AEAFPYLAYR EGHVAGIPAR
     LLRVGFVGEL GYEIHVPTRY GEALWDALMD AGKAFDIRPF GVETQRLLRL EKGHLIVSQD
     TDGMSHPGEL DLTWAVNRKK PFFVGCRSVD IVMAQPQTRK LVGFKLPLNS TKPEEGHLVL
     KGDKITGNVT SCEYSSASQA IIGLAFADIA DSEPGSRISI RVEGEEIMAD VVKLPFYDPE
     NLRQEM
//