ID   A0A1H9DUJ8_9FIRM        Unreviewed;       338 AA.
AC   A0A1H9DUJ8;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 13.
DE   SubName: Full=N-acetylneuraminate synthase {ECO:0000313|EMBL:SEQ16977.1};
GN   ORFNames=SAMN02910369_01312 {ECO:0000313|EMBL:SEQ16977.1};
OS   Lachnospiraceae bacterium NE2001.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=1520823 {ECO:0000313|EMBL:SEQ16977.1, ECO:0000313|Proteomes:UP000199680};
RN   [1] {ECO:0000313|EMBL:SEQ16977.1, ECO:0000313|Proteomes:UP000199680}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NE2001 {ECO:0000313|EMBL:SEQ16977.1,
RC   ECO:0000313|Proteomes:UP000199680};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FOEK01000008; SEQ16977.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H9DUJ8; -.
DR   STRING; 1520823.SAMN02910369_01312; -.
DR   Proteomes; UP000199680; Unassembled WGS sequence.
DR   GO; GO:0016051; P:carbohydrate biosynthetic process; IEA:InterPro.
DR   CDD; cd11615; SAF_NeuB_like; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   Gene3D; 3.90.1210.10; Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain; 1.
DR   InterPro; IPR006190; AFP_Neu5c_C.
DR   InterPro; IPR036732; AFP_Neu5c_C_sf.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR020007; N-AcNeuraminate_synthase.
DR   InterPro; IPR013132; Neu5Ac_N.
DR   NCBIfam; TIGR03569; NeuB_NnaB; 1.
DR   PANTHER; PTHR42966; N-ACETYLNEURAMINATE SYNTHASE; 1.
DR   PANTHER; PTHR42966:SF1; SIALIC ACID SYNTHASE; 1.
DR   Pfam; PF03102; NeuB; 1.
DR   SUPFAM; SSF51269; AFP III-like domain; 1.
DR   SUPFAM; SSF51569; Aldolase; 1.
DR   PROSITE; PS50844; AFP_LIKE; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000199680}.
FT   DOMAIN          286..338
FT                   /note="AFP-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50844"
SQ   SEQUENCE   338 AA;  37540 MW;  6D6DC75A35949F31 CRC64;
     MLHKQINDNC LIIAEAGVNH NGNLEIAKEL CYAAKESGAD VVKFQTWNTD KLITQSVKMA
     DYQQNNVGKS ESQYDMLKRL ELSQDEFRDV KKYCDDIGIL FSSTADEKDS LDFLIEVGIP
     FIKIGSGDIG NIPYLRYMGS KGLPIILSTG MSSLADVDLS LQALRQGGAK DITILHCTTN
     YPCAYDEVNL RAMNTLHEAF HIPVGYSDHT IGTEVSVSAV ALGARVIEKH FTLDRNMEGP
     DHVASTEPEE FKHMVKQIRN IEKALGDGVK QMSFSERSIK TVVTKRIVAS KPIVENEPFT
     KDNLCVKRSS EGEIASMWDV VIGKKAKKSY EVDQGIEL
//