ID A0A1H9GLQ0_9BACT Unreviewed; 663 AA.
AC A0A1H9GLQ0;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Two-component sensor histidine kinase, contains HisKA and HATPase domains {ECO:0000313|EMBL:SEQ50990.1};
GN ORFNames=SAMN05444359_11113 {ECO:0000313|EMBL:SEQ50990.1};
OS Neolewinella agarilytica.
OC Bacteria; Bacteroidota; Saprospiria; Saprospirales; Lewinellaceae;
OC Neolewinella.
OX NCBI_TaxID=478744 {ECO:0000313|EMBL:SEQ50990.1, ECO:0000313|Proteomes:UP000199021};
RN [1] {ECO:0000313|Proteomes:UP000199021}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 24740 {ECO:0000313|Proteomes:UP000199021};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FOFB01000011; SEQ50990.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H9GLQ0; -.
DR STRING; 478744.SAMN05444359_11113; -.
DR InParanoid; A0A1H9GLQ0; -.
DR Proteomes; UP000199021; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR011495; Sig_transdc_His_kin_sub2_dim/P.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR41523:SF7; ETHYLENE RESPONSE SENSOR PROTEIN; 1.
DR PANTHER; PTHR41523; TWO-COMPONENT SYSTEM SENSOR PROTEIN; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF07568; HisKA_2; 1.
DR Pfam; PF13424; TPR_12; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00028; TPR; 5.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Kinase {ECO:0000313|EMBL:SEQ50990.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000199021};
KW Transferase {ECO:0000313|EMBL:SEQ50990.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 430..450
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 476..663
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 381..419
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 663 AA; 75242 MW; 388C5CD284B3F468 CRC64;
MSHEVYVYDD FYPFSTYLAT HTVKSSYCLL ALCLLTFHCT RVSAQKANFE IYRDSIYRII
DTARSESEKF LQYSRIHDKL SPKDTALVLA YQDTMRSFKG KVDDDFFEAT YNFQLAWTLR
LQRRFTEARP VIKKTIEAYK RLDSVRFAAS IGRAHQMGTI IGLATQDLAF GHRQATQAIE
KFRSVTGEED NLAGTLSNLG SILMQTGLTE EALSPLRESE RMYRKAKRPD RYFHPVLNQG
NAHNTMGNRD SAVYHYERAL AAIDEQSRPN PGQRAFVQTN LGTVYLRQGK LADARDQLES
ASITFEKLGA KREYASAAGN LIVVYNKLGE HRKARDIGQQ ALNSAAKFPE VKRKILESQI
TTFINLREPD STQAYLDAFL KATNERNEAQ LEKSVANAEA QFQNDLKVAE IERLELEDQV
SQDRITRQKW LLIGAALILA LLSFLAYGLF RQRRRIEKQK DTIAKALKEK ETLLKEIHHR
VKNNLQMVSS LLSLQGRYLE DDGAKAALKM GNSRVRSMAL IHQKLYLTDE VNTLINARDY
LEKLVTELVK NLKRPDLELA LLLDVEDTEL DIDRMIPLGL IVNELVTNAL KYAYDGRESG
RLSIKLQPEG EGHSLTVQDD GVGMPEESRT NSFGLHLVES LVDQLGGKLQ RQEGKGAGLE
LSF
//
