ID A0A1H9GYZ1_9ACTN Unreviewed; 615 AA.
AC A0A1H9GYZ1;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN ORFNames=SAMN05216481_1106 {ECO:0000313|EMBL:SEQ55213.1};
OS Streptomyces radiopugnans.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=403935 {ECO:0000313|EMBL:SEQ55213.1, ECO:0000313|Proteomes:UP000199055};
RN [1] {ECO:0000313|EMBL:SEQ55213.1, ECO:0000313|Proteomes:UP000199055}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 4.3519 {ECO:0000313|EMBL:SEQ55213.1,
RC ECO:0000313|Proteomes:UP000199055};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine
CC residues in N-acetyl-beta-D-hexosaminides.; EC=3.2.1.52;
CC Evidence={ECO:0000256|ARBA:ARBA00001231};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 3 family.
CC {ECO:0000256|ARBA:ARBA00005336, ECO:0000256|RuleBase:RU361161}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FOET01000010; SEQ55213.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H9GYZ1; -.
DR STRING; 403935.SAMN05216481_1106; -.
DR Proteomes; UP000199055; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.1700; Glycoside hydrolase family 3 C-terminal domain; 1.
DR Gene3D; 3.20.20.300; Glycoside hydrolase, family 3, N-terminal domain; 1.
DR InterPro; IPR019800; Glyco_hydro_3_AS.
DR InterPro; IPR002772; Glyco_hydro_3_C.
DR InterPro; IPR036881; Glyco_hydro_3_C_sf.
DR InterPro; IPR001764; Glyco_hydro_3_N.
DR InterPro; IPR036962; Glyco_hydro_3_N_sf.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR006311; TAT_signal.
DR PANTHER; PTHR30480:SF13; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR30480; BETA-HEXOSAMINIDASE-RELATED; 1.
DR Pfam; PF00933; Glyco_hydro_3; 1.
DR Pfam; PF01915; Glyco_hydro_3_C; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF52279; Beta-D-glucan exohydrolase, C-terminal domain; 1.
DR PROSITE; PS00775; GLYCOSYL_HYDROL_F3; 1.
DR PROSITE; PS51318; TAT; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|RuleBase:RU361161};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361161};
KW Reference proteome {ECO:0000313|Proteomes:UP000199055};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..36
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 37..615
FT /note="beta-N-acetylhexosaminidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5039273298"
FT DOMAIN 66..403
FT /note="Glycoside hydrolase family 3 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00933"
FT DOMAIN 443..615
FT /note="Glycoside hydrolase family 3 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF01915"
SQ SEQUENCE 615 AA; 63941 MW; C3FBEA149BA6F39E CRC64;
MQQPATPSRR QALATGLFGV TAALTASAAL SSPANADTGA AAGSAAGSGT DRARARARAL
VRRMSLEDKV GQLFVVEVYG QAADTVSAGN RTLYGVDTPA EVIAKYRPGG VIYFDARRGP
DNVRDPLQTA RLSNGLQRAA GRAGARVPLL VSIDQEGGSV VYRLTDPATL LPGNMALAAG
RSTADTRRSA EIIGLELAAM GVNQNYAPVA DVNVNPENPV IGVRSFGSDP ALCASLVDAS
VSGYHRGRVA SAAKHFPGHG DTDTDSHTGL PRIDHTREEL ESIDLPPFRA AIARGVDTIM
TAHIVVPALD PSGVPATMSR PIVTGLLREE LGFEGLIVTD ALDMQGASGQ FPPDVAPVQA
LRAGCDQLVL APKLDTAYGA VLEAVRSGEI PVSRLDASVE RILAHKLRRD LFRHPYVDEQ
RAVRTVGAER HRTDAQAITD RTVTLVRNEG SLLPLSSGAR SVLVTGWGVG TTRSLADAVA
ERPGQSATVL ETGAIPSAGR ITEAADAAAG HGLVIVSVNA AAAGSEKGAA QARLVRALMD
TGTPVVAVAV RNPYDIRRFP GVPAYLATYS YGAPSLRAAV RTVYGDLSPA GRLPVAVPDL
DSTGTLYPFG HGLAY
//
