ID   A0A1H9IC05_9SPHN        Unreviewed;       348 AA.
AC   A0A1H9IC05;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   SubName: Full=2-oxoisovalerate dehydrogenase E1 component beta subunit {ECO:0000313|EMBL:SEQ72080.1};
GN   ORFNames=SAMN05518866_102260 {ECO:0000313|EMBL:SEQ72080.1};
OS   Sphingobium sp. YR768.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Sphingobium.
OX   NCBI_TaxID=1884365 {ECO:0000313|EMBL:SEQ72080.1, ECO:0000313|Proteomes:UP000199142};
RN   [1] {ECO:0000313|Proteomes:UP000199142}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YR768 {ECO:0000313|Proteomes:UP000199142};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC         Evidence={ECO:0000256|ARBA:ARBA00001964};
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DR   EMBL; FOGE01000002; SEQ72080.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H9IC05; -.
DR   STRING; 1884365.SAMN05518866_102260; -.
DR   Proteomes; UP000199142; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   CDD; cd07036; TPP_PYR_E1-PDHc-beta_like; 1.
DR   Gene3D; 3.40.50.920; -; 1.
DR   Gene3D; 3.40.50.970; -; 1.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR009014; Transketo_C/PFOR_II.
DR   InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR   InterPro; IPR033248; Transketolase_C.
DR   PANTHER; PTHR42980:SF1; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR42980; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA-RELATED; 1.
DR   Pfam; PF02779; Transket_pyr; 1.
DR   Pfam; PF02780; Transketolase_C; 1.
DR   SMART; SM00861; Transket_pyr; 1.
DR   SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR   SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000199142}.
FT   DOMAIN          15..190
FT                   /note="Transketolase-like pyrimidine-binding"
FT                   /evidence="ECO:0000259|SMART:SM00861"
SQ   SEQUENCE   348 AA;  37934 MW;  48ED7B25E23BA43E CRC64;
     MTDDVIEAVA ETTQMNMIQA INSAMDVMMA RDPDVVVMGE DVGFFGGVFR ATAGLQQKYG
     KNRVFDTPIT ECGIIGVAVG IGAYGLRPVP EIQFADYIYP ALDQLVSEAA RLRYRSAGEF
     IAPMTVRSPF GGGIFGGQTH SQSPEGIFTH CSGIKTVIPS TPYDAKGLLI AAIEDNDPTL
     FFEPKRIYNG PFDGHYDTPA TSWAGHADAQ VPTGYYRIPL GTARIARAGE ALTILCYGTM
     VHVVENTVAE MGIDAEIVDL RSLVPLDIDT IEASVKKTGR CLIVHEATRT SGFGAELLAQ
     VQERCFYHLE APIERVTGFD TPYPHSLEWA YFPGPVRIRE AITKIMKD
//