ID A0A1H9J5C4_9BURK Unreviewed; 612 AA.
AC A0A1H9J5C4;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE RecName: Full=diguanylate cyclase {ECO:0000256|ARBA:ARBA00012528};
DE EC=2.7.7.65 {ECO:0000256|ARBA:ARBA00012528};
GN ORFNames=SAMN02982919_01312 {ECO:0000313|EMBL:SEQ82080.1};
OS Giesbergeria anulus.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Giesbergeria.
OX NCBI_TaxID=180197 {ECO:0000313|EMBL:SEQ82080.1, ECO:0000313|Proteomes:UP000199766};
RN [1] {ECO:0000313|EMBL:SEQ82080.1, ECO:0000313|Proteomes:UP000199766}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35958 {ECO:0000313|EMBL:SEQ82080.1,
RC ECO:0000313|Proteomes:UP000199766};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FOGD01000002; SEQ82080.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H9J5C4; -.
DR STRING; 180197.SAMN02982919_01312; -.
DR Proteomes; UP000199766; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 2.60.40.2380; -; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR InterPro; IPR011623; 7TMR_DISM_rcpt_extracell_dom1.
DR InterPro; IPR011622; 7TMR_DISM_rcpt_extracell_dom2.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR45138:SF9; DIGUANYLATE CYCLASE DGCM-RELATED; 1.
DR PANTHER; PTHR45138; REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM; 1.
DR Pfam; PF07695; 7TMR-DISM_7TM; 1.
DR Pfam; PF07696; 7TMR-DISMED2; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000199766};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..612
FT /note="diguanylate cyclase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5011663461"
FT TRANSMEM 184..202
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 209..227
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 247..265
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 277..299
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 305..325
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 337..356
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 368..389
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 473..610
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT COILED 389..438
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 612 AA; 68114 MW; 4BC5B4BD202182C3 CRC64;
MTRRCLLLIL LLLGCCQKWA LAVEIRAYAG KTPLVSDIEA LEDRTGQLTI EAVRQLAQAG
RFTPVSNADG DLNFGFTASA YWLRIRLQRQ PEAASRWLLE VPYGQINTLQ WYPPQGEVLS
TGNDLPLSSR PVFHRHFVFP VELDTTEQVF YLRATSSYSL TLPLVLWNIK GFLRHEQGEL
IWQFLYYGAL LSLLLYNFLL YCSLGDKRFL FYSLYAAFLG LGMLAGNGYG RLYLWTEAPA
FDAISQSSIF CLAALFGAHF TRLFLQTGQR APHLDRWLQG HAVAFLLLAC GFGASLYWAV
PILWLNQWML FNALGMGAAI AVAGWRVQRT GAHHIRFFLL AWGVLWFGVV VAGLRAFGWL
PSNVLTSYAL QIASAFEMLL LSLALADIIH AERRSREQSQ QQALQAQQQM LEVLRHSEEK
LERAVRERTA ELERANAQLQ VLGTTDSLTG LANRRRFDQV LANAWAHASS SGQPIALIML
DVDHFKQYND HYGHVAGDQC LRQVGQVLAQ YVELPEELVA RYGGEEFAVI IMGRGATEVC
ALAERLRSGI EGLAIPHACA SPGVVTISLG VASLVPTALG DGPDALIRIA DAELYRAKQS
GRNRVQCAHG FA
//
