ID   A0A1H9JFQ9_9ACTN        Unreviewed;       949 AA.
AC   A0A1H9JFQ9;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   SubName: Full=Phosphopantetheine attachment site {ECO:0000313|EMBL:SEQ85831.1};
DE   Flags: Fragment;
GN   ORFNames=SAMN05216481_117103 {ECO:0000313|EMBL:SEQ85831.1};
OS   Streptomyces radiopugnans.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=403935 {ECO:0000313|EMBL:SEQ85831.1, ECO:0000313|Proteomes:UP000199055};
RN   [1] {ECO:0000313|EMBL:SEQ85831.1, ECO:0000313|Proteomes:UP000199055}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 4.3519 {ECO:0000313|EMBL:SEQ85831.1,
RC   ECO:0000313|Proteomes:UP000199055};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC         Evidence={ECO:0000256|ARBA:ARBA00001957};
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DR   EMBL; FOET01000017; SEQ85831.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H9JFQ9; -.
DR   STRING; 403935.SAMN05216481_117103; -.
DR   Proteomes; UP000199055; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR   GO; GO:0017000; P:antibiotic biosynthetic process; IEA:UniProt.
DR   GO; GO:0008610; P:lipid biosynthetic process; IEA:UniProt.
DR   GO; GO:1901362; P:organic cyclic compound biosynthetic process; IEA:UniProt.
DR   CDD; cd19543; DCL_NRPS; 1.
DR   CDD; cd19540; LCL_NRPS-like; 1.
DR   Gene3D; 1.10.1200.10; ACP-like; 1.
DR   Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 2.
DR   Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 2.
DR   InterPro; IPR036736; ACP-like_sf.
DR   InterPro; IPR023213; CAT-like_dom_sf.
DR   InterPro; IPR001242; Condensatn.
DR   InterPro; IPR020806; PKS_PP-bd.
DR   InterPro; IPR009081; PP-bd_ACP.
DR   InterPro; IPR006162; Ppantetheine_attach_site.
DR   PANTHER; PTHR45398; ENZYME, PUTATIVE (JCVI)-RELATED; 1.
DR   PANTHER; PTHR45398:SF1; ENZYME, PUTATIVE (JCVI)-RELATED; 1.
DR   Pfam; PF00668; Condensation; 2.
DR   Pfam; PF00550; PP-binding; 1.
DR   SMART; SM00823; PKS_PP; 1.
DR   SUPFAM; SSF47336; ACP-like; 1.
DR   SUPFAM; SSF52777; CoA-dependent acyltransferases; 4.
DR   PROSITE; PS50075; CARRIER; 1.
DR   PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE   4: Predicted;
KW   Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199055}.
FT   DOMAIN          471..546
FT                   /note="Carrier"
FT                   /evidence="ECO:0000259|PROSITE:PS50075"
FT   REGION          449..473
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         949
FT                   /evidence="ECO:0000313|EMBL:SEQ85831.1"
SQ   SEQUENCE   949 AA;  102686 MW;  1B45A18F8C9421CB CRC64;
     MTNKELFEDI LPLAPLQEGM LFHATYDQDA LDVYTVRLAI DFEGPFDLDV FRDAVRALLV
     RRSNLRAGFL SENLSRPVQV VPREFETPVV VHDLSGLGED ERAARLAELV AAQESVRFDL
     TNPPLLRFTV VRLAERGWRL MFGCHHILLD GWSMPLVLGE LFELYQRGGD PAGLPPAPPF
     KLYLAWLRKQ DKQAGLDAWR AALDGLDGAT LVAPEAGDDV AALPGRVTAD LSAARSAELA
     ALARRLGITV NTMVQVAWGL LLSRLTGADD IVFGATVSGR PPEIEGVENI VGLFVNTVPV
     RVRLDGQESL RDLLLRVQDE QSALLDHHYI GLTEVQRAAG HGRLFDSLVA FESYPVDADS
     LQGSLGDLTV TGVRGADATH YPLTLIVVPG ERMQLRLGFR EGLFTQDTAN GLLAGLERLL
     EAVAEDGARP VAEVTASVAL PEGWTVPRPA PEATGGASVS DLTAVSGGGR APRTPHEEVL
     CGLFAEALGV PSVSIDDNFF DLGGHSLLAT RLVSRVRSVF EIELPVRALF DAQTVAALAE
     RVVDSATGGR PPVRPAERPE RIPLSFAQRR LWFLNRMEGP SGTYNIPLAV RLTGTLDTTA
     LGAALQDVIG RHESLRTVFP DTDGEPWQQI VPAQDATLPL DLTEVNAEDL PAALAQAAST
     GFDLATDLPV RAWLFRLTDT EHVLCLVVHH IAGDGWSQAP LARDLGQAYR ARLTGTAPTW
     QPLPAQYADY ALWQHDTLGD ENDPDSPIAA QLAYWRQALD GLPDELNLPV DRARPAVSSY
     RGGLVTTELG ARLHRDLTGL ARSTRSSLFM VLQAGVAGLL SRLGAGTDIP LGTAIAGRTD
     TALDDLVGFF VNTLVLRTDT SGDPGLRELV ERTRTTDLAA YAHQDLPFEQ LVHALQPARS
     LARHPLFQVM IVLQNNTQAS LDLPGLTAHP IDGELGAAKF DLGFNFIER
//