ID A0A1H9JPI1_9SPHN Unreviewed; 456 AA.
AC A0A1H9JPI1;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Alanine or glycine:cation symporter, AGCS family {ECO:0000313|EMBL:SEQ88698.1};
GN ORFNames=SAMN05518866_103242 {ECO:0000313|EMBL:SEQ88698.1};
OS Sphingobium sp. YR768.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingobium.
OX NCBI_TaxID=1884365 {ECO:0000313|EMBL:SEQ88698.1, ECO:0000313|Proteomes:UP000199142};
RN [1] {ECO:0000313|Proteomes:UP000199142}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YR768 {ECO:0000313|Proteomes:UP000199142};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|RuleBase:RU363064}; Multi-pass membrane protein
CC {ECO:0000256|RuleBase:RU363064}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the alanine or glycine:cation symporter (AGCS)
CC (TC 2.A.25) family. {ECO:0000256|ARBA:ARBA00009261,
CC ECO:0000256|RuleBase:RU363064}.
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DR EMBL; FOGE01000003; SEQ88698.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H9JPI1; -.
DR STRING; 1884365.SAMN05518866_103242; -.
DR OrthoDB; 9806926at2; -.
DR Proteomes; UP000199142; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005283; F:amino acid:sodium symporter activity; IEA:InterPro.
DR InterPro; IPR001463; Na/Ala_symport.
DR NCBIfam; TIGR00835; agcS; 1.
DR PANTHER; PTHR30330; AGSS FAMILY TRANSPORTER, SODIUM-ALANINE; 1.
DR PANTHER; PTHR30330:SF3; TRANSCRIPTIONAL REGULATOR, LRP FAMILY-RELATED; 1.
DR Pfam; PF01235; Na_Ala_symp; 1.
DR PRINTS; PR00175; NAALASMPORT.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|RuleBase:RU363064};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363064};
KW Reference proteome {ECO:0000313|Proteomes:UP000199142};
KW Symport {ECO:0000256|RuleBase:RU363064};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU363064};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU363064};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363064}.
FT TRANSMEM 29..50
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 75..100
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 106..128
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 159..178
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 198..219
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 231..249
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 255..276
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 316..336
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 356..379
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 425..443
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
SQ SEQUENCE 456 AA; 47910 MW; 6F3B9379B78D24C1 CRC64;
MENFNAFVDG LSAAVFFKVP LFGAQIELIV LYLALPMLFF TLWLGFPNVT QVGRAIRILR
SQPQHGEAKG DVSQWAALST ALSGTIGLGN IAGVAVALTM GGPGAILWMF IIGWFAMTVK
MAEVTLGLKY RVFDSRGHVH GGPMYVLKAV GAARGWPKLG IVLGGAYAFF ALFGAIPMVQ
VNQSFAQVKV VTGITNGWAY GVFLAGAVAL VTLGGAAWLG EVSKRLTPLK VAVYLAGVAA
ILILHVTEIP SALALIWNGA WSGGAMTGGA VGAFVAGMRR AVFASEAGVG SAVMAHSLAR
AEHPVSEGLV ALLEPLLGTM IVCALGGLAL VVAGTWNTGL EGIAITSAAF AKVSPWFPWL
LAVVVFLFAY STLVAWGFYG LQAWGYLFGN GPKAQWVYKI LYVVALPPAA AIDLGRVVGI
VDSSFFLMAI PNVIALYLCA GELRRDVRNY LAKGEA
//
