ID A0A1H9JXS6_9GAMM Unreviewed; 747 AA.
AC A0A1H9JXS6;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=SAMN03080615_03213 {ECO:0000313|EMBL:SEQ91627.1};
OS Amphritea atlantica.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Oceanospirillaceae; Amphritea.
OX NCBI_TaxID=355243 {ECO:0000313|EMBL:SEQ91627.1, ECO:0000313|Proteomes:UP000198749};
RN [1] {ECO:0000313|Proteomes:UP000198749}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 18887 {ECO:0000313|Proteomes:UP000198749};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FOGB01000011; SEQ91627.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H9JXS6; -.
DR STRING; 355243.SAMN03080615_03213; -.
DR OrthoDB; 1931120at2; -.
DR Proteomes; UP000198749; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 1.
DR CDD; cd12914; PDC1_DGC_like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR InterPro; IPR033479; dCache_1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR029151; Sensor-like_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43065:SF58; C4-DICARBOXYLATE TRANSPORT SENSOR PROTEIN DCTB; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF02743; dCache_1; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF13426; PAS_9; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR SUPFAM; SSF103190; Sensory domain-like; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|SAM:Coils}; Kinase {ECO:0000313|EMBL:SEQ91627.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000313|EMBL:SEQ91627.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 307..326
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 348..393
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 423..473
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 525..738
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 461..513
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 747 AA; 83815 MW; 9AF58BCE2684937D CRC64;
MVRTRSRLLW ALLLTALFIL VIYQTVAISR SRAVDDLQRS ASADLNRYIL SLQQELDRYK
DLPKLLSTHS ELVNLLLLPG SEGIHGANLY LEKVNDTIGA SDTYLMDTQG NTLAASNWSK
PQTFVGRNFS FRPYFRDAME GRGGRYFALG TTSKKRGYFF SYPVEYRGTI LGVIVVKIDL
NDIETDWNDP LTDILVTDED GVIFISTRAE WKFRTLKPLP QEDLQRIISS LRYGDHQLTS
LSIVERKKFQ DSELVTLIEG DTIANGALDG IETRQYLQQT RAVPEAGFNV SILADLKPVD
KRVLSNALLA GFIYSALVFL VLLLLARRRI ARERARFKLQ QTRALERSEA RVRAIIDNTH
AGLITLDAHG LIESFNPTAE KLFGYRSDVI VGEYFSKLIG YQDRAVCWQH ISQESGARQL
SELMVEVSSV RADGSQFPVE LIIGRMSDSS VNRFVVTIHD ITERKENEEQ LREARDQLEQ
RVSERTEDLT RANERLLQEV EEHKHTQNEL IQTAKLAVIG QMSAGINHEL NQPLTAIRSY
ADNALSFLKL GKTEKVSSNL NEISGLTVRM AKIIAPLKEF SRKTSGQATL VSLKAVRDGA
MSIMYGRLDR ENVKIEWPDK LDQIFVLGDM LRLEQVVVNL ISNALQAMEG GTEKWIEISI
QRQDDRLNLC FRDHGPGIPQ SELGKVFEPF YTTKKAGQGL GLGLSISHRI IESMDGDLSV
SNHPMGGAVF TISLPAADAP ASVVGLE
//
