ID   A0A1H9K8M2_9FLAO        Unreviewed;       493 AA.
AC   A0A1H9K8M2;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=Deoxyribodipyrimidine photo-lyase family protein (Cryptochrome) {ECO:0000313|EMBL:SEQ95510.1};
GN   ORFNames=SAMN05421824_2658 {ECO:0000313|EMBL:SEQ95510.1};
OS   Hyunsoonleella jejuensis.
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae.
OX   NCBI_TaxID=419940 {ECO:0000313|EMBL:SEQ95510.1, ECO:0000313|Proteomes:UP000198999};
RN   [1] {ECO:0000313|EMBL:SEQ95510.1, ECO:0000313|Proteomes:UP000198999}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 21035 {ECO:0000313|EMBL:SEQ95510.1,
RC   ECO:0000313|Proteomes:UP000198999};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|PIRSR:PIRSR602081-1};
CC       Note=Binds 1 FAD per subunit. {ECO:0000256|PIRSR:PIRSR602081-1};
CC   -!- SIMILARITY: Belongs to the DNA photolyase family.
CC       {ECO:0000256|RuleBase:RU004182}.
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DR   EMBL; FOFN01000004; SEQ95510.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H9K8M2; -.
DR   STRING; 419940.SAMN05421824_2658; -.
DR   OrthoDB; 9772484at2; -.
DR   Proteomes; UP000198999; Unassembled WGS sequence.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   GO; GO:0097159; F:organic cyclic compound binding; IEA:UniProt.
DR   GO; GO:0051716; P:cellular response to stimulus; IEA:UniProt.
DR   GO; GO:0006139; P:nucleobase-containing compound metabolic process; IEA:UniProt.
DR   GO; GO:0006950; P:response to stress; IEA:UniProt.
DR   Gene3D; 1.25.40.80; -; 1.
DR   Gene3D; 1.10.579.10; DNA Cyclobutane Dipyrimidine Photolyase, subunit A, domain 3; 1.
DR   Gene3D; 3.40.50.620; HUPs; 1.
DR   InterPro; IPR036134; Crypto/Photolyase_FAD-like_sf.
DR   InterPro; IPR036155; Crypto/Photolyase_N_sf.
DR   InterPro; IPR005101; Cryptochr/Photolyase_FAD-bd.
DR   InterPro; IPR002081; Cryptochrome/DNA_photolyase_1.
DR   InterPro; IPR018394; DNA_photolyase_1_CS_C.
DR   InterPro; IPR006050; DNA_photolyase_N.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   PANTHER; PTHR11455; CRYPTOCHROME; 1.
DR   PANTHER; PTHR11455:SF9; CRYPTOCHROME-1; 1.
DR   Pfam; PF00875; DNA_photolyase; 1.
DR   Pfam; PF03441; FAD_binding_7; 1.
DR   PRINTS; PR00147; DNAPHOTLYASE.
DR   SUPFAM; SSF48173; Cryptochrome/photolyase FAD-binding domain; 1.
DR   SUPFAM; SSF52425; Cryptochrome/photolyase, N-terminal domain; 1.
DR   PROSITE; PS00394; DNA_PHOTOLYASES_1_1; 1.
DR   PROSITE; PS51645; PHR_CRY_ALPHA_BETA; 1.
PE   3: Inferred from homology;
KW   Chromophore {ECO:0000256|ARBA:ARBA00022991, ECO:0000256|RuleBase:RU004182};
KW   FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|PIRSR:PIRSR602081-1};
KW   Flavoprotein {ECO:0000256|ARBA:ARBA00022630, ECO:0000256|PIRSR:PIRSR602081-
KW   1}; Lyase {ECO:0000313|EMBL:SEQ95510.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198999}.
FT   DOMAIN          6..136
FT                   /note="Photolyase/cryptochrome alpha/beta"
FT                   /evidence="ECO:0000259|PROSITE:PS51645"
FT   BINDING         217
FT                   /ligand="FAD"
FT                   /ligand_id="ChEBI:CHEBI:57692"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR602081-1"
FT   BINDING         268
FT                   /ligand="FAD"
FT                   /ligand_id="ChEBI:CHEBI:57692"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR602081-1"
SQ   SEQUENCE   493 AA;  58284 MW;  2127DB3CFDBA42E7 CRC64;
     MTTKPPITVV WLKRDLRLHD NEAIYNALKA NKPTLLLYCF EPLLMNDPHY SERHWNFIKE
     SIVDLNKELE AYNSKILTVQ CDIIAAINQL QTLYSISEIY SHQETGILVT FERDKNFKRY
     CKNNLITWHE NINNGVQRGL KNRDNWNELV DAFYAVEPLK FTPKNNQLLT IEAIKDLETL
     FKIPNLNAQQ FTPFQKGGRT TGKRYLSTFF EERHRDYMLH ISKPELARTS CSRISPYIAW
     GNLSVREVYH QAYHLKETSK HKKALEAFMS RLRWQTHFIQ KFEMEHTMEE ASLNKGFHKL
     KKSISKDYQQ AWKTGQTGYP MVDACMRCLN ETGYLNFRMR ALVVSFFTHN LWQPWQEATT
     HLSQMFLDFE PGIHFPQLQM QAGETGINML RIYNPVKNSL EHDPNATFIK KWVPELEKLD
     TPFAHQPYLM TEMEQQFYGF NLGKDYPKPI VDLETTRKKA GDTLWTLRKD KTVLEESKRI
     LRKHTRNKRL SKS
//