ID A0A1H9KNM5_9ACTN Unreviewed; 317 AA.
AC A0A1H9KNM5;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=ABC-2 type transport system ATP-binding protein {ECO:0000313|EMBL:SER00453.1};
GN ORFNames=SAMN05216481_1267 {ECO:0000313|EMBL:SER00453.1};
OS Streptomyces radiopugnans.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=403935 {ECO:0000313|EMBL:SER00453.1, ECO:0000313|Proteomes:UP000199055};
RN [1] {ECO:0000313|EMBL:SER00453.1, ECO:0000313|Proteomes:UP000199055}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 4.3519 {ECO:0000313|EMBL:SER00453.1,
RC ECO:0000313|Proteomes:UP000199055};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FOET01000026; SER00453.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H9KNM5; -.
DR STRING; 403935.SAMN05216481_1267; -.
DR Proteomes; UP000199055; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0043215; P:daunorubicin transport; IEA:InterPro.
DR GO; GO:1900753; P:doxorubicin transport; IEA:InterPro.
DR GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR005894; DrrA.
DR InterPro; IPR025302; DUF4162.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR01188; drrA; 1.
DR PANTHER; PTHR42711; ABC TRANSPORTER ATP-BINDING PROTEIN; 1.
DR PANTHER; PTHR42711:SF18; DOXORUBICIN RESISTANCE ATP-BINDING PROTEIN DRRA; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR Pfam; PF13732; DUF4162; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 4: Predicted;
KW Antibiotic resistance {ECO:0000256|ARBA:ARBA00023251};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:SER00453.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000199055};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 6..236
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 317 AA; 33292 MW; D950D6A4B474A78C CRC64;
MAKPMIEAIN VTKTFGDVAA LDGVNVSVPE GSIHGLLGHN GAGKTTLVNI LSTLLEPTGG
TARICGLDVT AKAQKVRRCI GLTGQFASVD EQLSGRDNLT LIARLLGAGK RQAHARADEL
LELFELSQAA KRPVSQYSGG MRRRLDIAAS LVGSPQVIFL DEPTTGLDPN SRIGVWEIVK
RLAKDGVAVL LTTQYLEEAD QLCDRITLLS KGRVVAGGTP DELKADVGQR MVTVTLSAQS
EVPTAVKALG ATGIQATPQE SGSTISVPVA ASADLAAIVR TLNEAHTEIT ELGFSEPTLD
DVYLRLTHEP TGTSVPA
//
