ID   A0A1H9LP19_9ACTN        Unreviewed;       831 AA.
AC   A0A1H9LP19;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=Biotin carboxylase {ECO:0000313|EMBL:SER12979.1};
GN   ORFNames=SAMN04487983_1011137 {ECO:0000313|EMBL:SER12979.1};
OS   Streptomyces sp. yr375.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1761906 {ECO:0000313|EMBL:SER12979.1, ECO:0000313|Proteomes:UP000198568};
RN   [1] {ECO:0000313|EMBL:SER12979.1, ECO:0000313|Proteomes:UP000198568}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YR375 {ECO:0000313|EMBL:SER12979.1,
RC   ECO:0000313|Proteomes:UP000198568};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FOFF01000011; SER12979.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H9LP19; -.
DR   STRING; 1761906.SAMN04487983_1011137; -.
DR   OrthoDB; 3428978at2; -.
DR   Proteomes; UP000198568; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003824; F:catalytic activity; IEA:UniProt.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   Gene3D; 3.40.50.20; -; 1.
DR   Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR   Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 2.
DR   InterPro; IPR011761; ATP-grasp.
DR   InterPro; IPR013815; ATP_grasp_subdomain_1.
DR   PANTHER; PTHR43585:SF2; ATP-GRASP ENZYME FSQD; 1.
DR   PANTHER; PTHR43585; FUMIPYRROLE BIOSYNTHESIS PROTEIN C; 1.
DR   Pfam; PF13535; ATP-grasp_4; 1.
DR   SMART; SM01209; GARS_A; 1.
DR   SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 2.
DR   PROSITE; PS50975; ATP_GRASP; 2.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00409}; Ligase {ECO:0000256|ARBA:ARBA00022598};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00409}; Reference proteome {ECO:0000313|Proteomes:UP000198568}.
FT   DOMAIN          116..305
FT                   /note="ATP-grasp"
FT                   /evidence="ECO:0000259|PROSITE:PS50975"
FT   DOMAIN          532..729
FT                   /note="ATP-grasp"
FT                   /evidence="ECO:0000259|PROSITE:PS50975"
SQ   SEQUENCE   831 AA;  87910 MW;  D5052810249E8FB7 CRC64;
     MPEHVIIIHR WTDRYADYVA YIDHAAHRVS YVTTEQAVHH LPVDRAAGVR LVASTEHAKA
     VREAVDALAE RNGVPTRIVA LHESDLDLAA ELRAEFDLPG VRGEDLRPLR DKLLMARRLQ
     AAGLPVPATA PAPDHATVAA FAAEHGWPVL VKPRRGTASV GVTRLDSPQE LARYPFPRDT
     ALLVQPWLPD RILHVDGVFT GENLGVWRAS RYLTTCLDFT TGAPLGSVEI DDAQVLAGIG
     ELTAAVARAL FSGPSVFHLE LFESDETGAL TVLEIGARPG GAEVPFIWRE VHGIDLMAVA
     FAHQTGTPAP TEATAPADQS GPQLGRVGGW VLVPPSTPAP CRVRTATAPD DSGAYAQLLP
     ESGMLMRGGG YEHAGARFRF AGDSTADVET AVRRTMCDAA LVTTPVDLEA PARLVVVGCG
     NPPYRRYALD SLAALDSPDA PAGRVEAALV QPRALDWQRP YVADRFRQAD TSNTTGTTRA
     VAALLAGHPG PGAVLTWDET LLETTAEVAR RLGLPHMSPQ AVSGCRDKLT TRRLLAAAGV
     PSARFRHVHS RQDARAAAEA LGLPAVVKPR SLAGSIGVAL ATDPDQVGPA HDMAAASAFP
     GIDGLAGVIV EEYLSGDELS VDCAVFHGEV HVVNVARKRL GFAPYFEEVG HLVAPWQDEP
     WAVEVRSVVA AAHAALGIRT GLTHTELRLT ATGPRIVEVN GRLGGDFIPL LGALATGVDQ
     VAAAACIALG RTPDLTATRD RCAEVRFVYP DHDALVHGVD LTAAAAEPGI VHAISLAAPG
     TELRLPPRGI VPRLAALVAT GETPDACTAA LDRAEQAVRH TLTPLPLPER P
//