ID   A0A1H9M585_9SPHI        Unreviewed;       643 AA.
AC   A0A1H9M585;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 12.
DE   SubName: Full=NDP-sugar epimerase, includes UDP-GlcNAc-inverting 4,6-dehydratase FlaA1 and capsular polysaccharide biosynthesis protein EpsC {ECO:0000313|EMBL:SER18804.1};
GN   ORFNames=SAMN04488023_105107 {ECO:0000313|EMBL:SER18804.1};
OS   Pedobacter rhizosphaerae.
OC   Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC   Sphingobacteriaceae; Pedobacter.
OX   NCBI_TaxID=390241 {ECO:0000313|EMBL:SER18804.1, ECO:0000313|Proteomes:UP000199572};
RN   [1] {ECO:0000313|EMBL:SER18804.1, ECO:0000313|Proteomes:UP000199572}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 18610 {ECO:0000313|EMBL:SER18804.1,
RC   ECO:0000313|Proteomes:UP000199572};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the polysaccharide synthase family.
CC       {ECO:0000256|ARBA:ARBA00007430}.
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DR   EMBL; FOGG01000005; SER18804.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H9M585; -.
DR   STRING; 390241.SAMN04488023_105107; -.
DR   OrthoDB; 9803111at2; -.
DR   Proteomes; UP000199572; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd05237; UDP_invert_4-6DH_SDR_e; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR003869; Polysac_CapD-like.
DR   PANTHER; PTHR43318:SF1; POLYSACCHARIDE BIOSYNTHESIS PROTEIN EPSC-RELATED; 1.
DR   PANTHER; PTHR43318; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE; 1.
DR   Pfam; PF02719; Polysacc_synt_2; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199572};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        49..69
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        81..98
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        118..142
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          292..587
FT                   /note="Polysaccharide biosynthesis protein CapD-like"
FT                   /evidence="ECO:0000259|Pfam:PF02719"
SQ   SEQUENCE   643 AA;  73321 MW;  956866394BD42994 CRC64;
     MKKLIFPDKA HSRWLILLID QFIVVWTLFI SIVLTHTANY ADIFKLENYL YVGLYAIIAA
     AVFISLRIHT GIIRYSNTED ILRVFLAVFV SSLLFVGLNK ILAQRFELLW SQMDKALILN
     FFISSSLLIM LRISVKGIFY FFKELKSEDK EHILIYGSEK KAILIKKAIE QNEESNLCIV
     GFVDDNQDRI DKYLEQKKVF HSSAISFLKN KHGIKKILFA EDALNTLNKK KIVDTCINEG
     IKVIMVPPSN KWLYGKFDQH QLRDLKIEDL LEREAIKLNE KNILKELNGK CILVTGAAGS
     IGSEIVRQVL QYNPKSVILC DQAETPLHDL KLELEDSLQA KNVKIFMANV QNANRIRTLF
     EWYKPEIVFH AAAYKHVPMM ENNPAEAILT NVLGTKNMAD ISLEYGVEKF VMISTDKAVK
     PTNVMGASKR LAEIYIQSLN SPELTTTDSI SEGHHLRTRF VTTRFGNVLG SNGSVIPRFK
     SQIEKRGPIT VTHPDITRYF MTIPEAVQLV MEAGAMGQGG EIFLFDMGKP VKIVDLAINM
     IKLAGLVPYE DIDLVFTGLR PGEKLYEELL LSEEAMMETH HPKIKISQKV TYNFIYVNQI
     IKDLIELNQE GNDYNVVKKM KEIIPDYISN NSQYEDLDLL VAN
//