ID A0A1H9M759_9ACTN Unreviewed; 535 AA.
AC A0A1H9M759;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Transcriptional regulator, GntR family {ECO:0000313|EMBL:SER19534.1};
GN ORFNames=SAMN04487983_1012111 {ECO:0000313|EMBL:SER19534.1};
OS Streptomyces sp. yr375.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1761906 {ECO:0000313|EMBL:SER19534.1, ECO:0000313|Proteomes:UP000198568};
RN [1] {ECO:0000313|EMBL:SER19534.1, ECO:0000313|Proteomes:UP000198568}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YR375 {ECO:0000313|EMBL:SER19534.1,
RC ECO:0000313|Proteomes:UP000198568};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: In the C-terminal section; belongs to the class-I
CC pyridoxal-phosphate-dependent aminotransferase family.
CC {ECO:0000256|ARBA:ARBA00005384}.
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DR EMBL; FOFF01000012; SER19534.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H9M759; -.
DR STRING; 1761906.SAMN04487983_1012111; -.
DR Proteomes; UP000198568; Unassembled WGS sequence.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00609; AAT_like; 1.
DR CDD; cd07377; WHTH_GntR; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR004839; Aminotransferase_I/II.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR46577; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR PANTHER; PTHR46577:SF1; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR Pfam; PF00155; Aminotran_1_2; 1.
DR Pfam; PF00392; GntR; 1.
DR PRINTS; PR00035; HTHGNTR.
DR SMART; SM00345; HTH_GNTR; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50949; HTH_GNTR; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Reference proteome {ECO:0000313|Proteomes:UP000198568};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 68..136
FT /note="HTH gntR-type"
FT /evidence="ECO:0000259|PROSITE:PS50949"
SQ SEQUENCE 535 AA; 56706 MW; 0068DB74F5C12CF6 CRC64;
MVGGVEWVVL VAFRMTLCGL EANAIHGQFG EGGLENMTQW TSAVGAAQLA RLLKSQQDRP
AGPGTRRPPA YRALADGVRL LVLEGRVPVA ARLPAERELA LSLAVSRTTV AAAYEALRAE
GFLESRRGAG SWTAVPAGNP VPARGLEPLP PEALGSMIDL GCASLPAPEP WLTRAVQGAL
EELPPYAHTH GDYPAGLPAL RAMIAERYTA RGIPTMPEQV MVTTGAMGAI DAICHLFGGR
GERIAVESPS YANILQLMRE AGARLVPVAM AEGLAGWDMD RWRQVLRDAA PRIAYVVADF
HNPTGALADE DQRRRLVEAA RSAGTVLVAD ETMSELWLDD DVEMPRPVCG FDPAGSAVVT
VGSASKAFWA GMRIGWVRAA PDVIRSLVAA RAYADMGTPV LEQLAVNWLF STGGWEQAVE
LRRAQARGHR DDLVGALRRE LPEWEFTVPK GGLTLWVRAG GLSGSRLAEA GERVGLRVPS
GPRFGVDGAF EGYVRLPFTV GGAVADEAAA RLAAAARIVE SGGATAGEGP RTFVA
//
