ID A0A1H9N828_9PROT Unreviewed; 550 AA.
AC A0A1H9N828;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=diguanylate cyclase {ECO:0000256|ARBA:ARBA00012528};
DE EC=2.7.7.65 {ECO:0000256|ARBA:ARBA00012528};
GN ORFNames=SAMN05421690_101912 {ECO:0000313|EMBL:SER32084.1};
OS Nitrosomonas sp. Nm51.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC Nitrosomonadaceae; Nitrosomonas.
OX NCBI_TaxID=133720 {ECO:0000313|EMBL:SER32084.1, ECO:0000313|Proteomes:UP000198732};
RN [1] {ECO:0000313|EMBL:SER32084.1, ECO:0000313|Proteomes:UP000198732}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nm51 {ECO:0000313|EMBL:SER32084.1,
RC ECO:0000313|Proteomes:UP000198732};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FOGH01000019; SER32084.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H9N828; -.
DR STRING; 133720.SAMN05421690_101912; -.
DR OrthoDB; 9813903at2; -.
DR Proteomes; UP000198732; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd18773; PDC1_HK_sensor; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR InterPro; IPR033479; dCache_1.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR45138:SF9; DIGUANYLATE CYCLASE DGCM-RELATED; 1.
DR PANTHER; PTHR45138; REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM; 1.
DR Pfam; PF02743; dCache_1; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF00672; HAMP; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00304; HAMP; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000198732};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 288..308
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 309..362
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 412..545
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
SQ SEQUENCE 550 AA; 61264 MW; 7630731FD321D97A CRC64;
MKSIKSKIFV FALLSTLVPS LVLGLLSFHQ NEELIQDNVK RELRILASHA SREVDAWINQ
NIHEANSLTS AKIIIDALSN AARPQNAQSK SSPEILTHYL ISVQKKLDTI LELTVLDTNK
NIFASSSSRY VLNEPLQNNW LGGKITHTPV VSPPQLHAYY ETVTVSIILP IVSYDDYILG
QLAITYDLNN VKSVLKSSTK SPHGEILLVD SDGLLLLTSR AEITHPSILS PFAFDYLKNN
PGESTTFQNS SQENIIALAY TAKKLPLTVI ATKNHRDVYA AWLEQRNLYF ILVGISIFIV
AVIATYLGHS IVTPLQRLIN ATGQIVKGNL DIPITNVTQK DEVGKLAHMF NLMTEKLRQS
QSKILTANKA MQQKNQLLEK LSITDGLTGL YNRNKLNLII NEQLLRYQRN KRPFSVLMID
VDYFKELNDR LGHIAGDEIL AAVAKNLSQS IRSIDFAARY GGDEFIIILT ETNIQEAAIT
AERIRIKTSE IDCKTTNNKI QVTLSIGIIQ SEPEDTSPTT IISRADHALY KAKNAGRNQA
YAVQPVSILT
//
