ID   A0A1H9NIE3_9SPHN        Unreviewed;       594 AA.
AC   A0A1H9NIE3;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=TrkA-C domain-containing protein {ECO:0000313|EMBL:SER35734.1};
GN   ORFNames=SAMN05518866_109114 {ECO:0000313|EMBL:SER35734.1};
OS   Sphingobium sp. YR768.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Sphingobium.
OX   NCBI_TaxID=1884365 {ECO:0000313|EMBL:SER35734.1, ECO:0000313|Proteomes:UP000199142};
RN   [1] {ECO:0000313|Proteomes:UP000199142}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YR768 {ECO:0000313|Proteomes:UP000199142};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; FOGE01000009; SER35734.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H9NIE3; -.
DR   STRING; 1884365.SAMN05518866_109114; -.
DR   OrthoDB; 9809303at2; -.
DR   Proteomes; UP000199142; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR   Gene3D; 3.30.70.1450; Regulator of K+ conductance, C-terminal domain; 2.
DR   InterPro; IPR004680; Cit_transptr-like_dom.
DR   InterPro; IPR031312; Na/sul_symport_CS.
DR   InterPro; IPR006037; RCK_C.
DR   InterPro; IPR036721; RCK_C_sf.
DR   PANTHER; PTHR43652; BASIC AMINO ACID ANTIPORTER YFCC-RELATED; 1.
DR   PANTHER; PTHR43652:SF2; BASIC AMINO ACID ANTIPORTER YFCC-RELATED; 1.
DR   Pfam; PF03600; CitMHS; 1.
DR   Pfam; PF02080; TrkA_C; 1.
DR   SUPFAM; SSF116726; TrkA C-terminal domain-like; 2.
DR   PROSITE; PS01271; NA_SULFATE; 1.
DR   PROSITE; PS51202; RCK_C; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199142};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        6..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        35..51
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        57..79
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        153..174
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        186..208
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        404..437
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        457..481
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        488..506
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        512..529
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        536..554
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        574..593
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          215..299
FT                   /note="RCK C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51202"
FT   DOMAIN          304..388
FT                   /note="RCK C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51202"
SQ   SEQUENCE   594 AA;  62312 MW;  28DB447824B38D86 CRC64;
     MHFITALLGI YRAEIGLIIL AGMFVAFVRE RYSPTVIAVV GACAYGVLGL LDEKAMFSVF
     SNSAPLTVGA MFVLSGALIR TGVIGRIADL IMTRAERHPR IALAEVTLGT LALSAFLNNT
     PVVVLLIPIM FKLAQATGYP VKKLLIPMNV VAVLGGCLTL VGTSTNLVVA GIAAEQGLPR
     FSIFDISLYG AAGAAAGIVA LLCLSFLLPS DPPSIAGEDG GTAVQDYLTE LVVPQESDDI
     GREIGSLGLF GRSVQLLGLK RAGEVRRHDL EGEELHSGDR LIVRADGAAI MTLRESGRFD
     LGVAADSRTS AQEGTVVEAM VAPSHPSIGE RLLDIPFLHA LRVRIIGIHR ARHLPGPDLA
     DARIRGADRL LVAGGDDAMR ALKDNPHLIG VDVSRTRAFR PRKAWIAIAA MAGAVLLSAF
     DVVGIGLAAV IAVGLILITR CIDPEEAWGA IDGDTLILIF AMLAVGLALE QAGSVALMVG
     WITPLMQVAP GWSLVFIVYF AALLLSELLS NNAVAALLTP ITIALAHQLD VDARPLVIAL
     MIGASACFAT PIGYQTNALV YAAGDYRFAD FVRIGVPINI AVGLAVCSAL VLLG
//