ID   A0A1H9NZE3_9PSEU        Unreviewed;       571 AA.
AC   A0A1H9NZE3;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Dihydroxy-acid dehydratase {ECO:0000313|EMBL:SER41346.1};
GN   ORFNames=SAMN05216188_11177 {ECO:0000313|EMBL:SER41346.1};
OS   Lentzea xinjiangensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Lentzea.
OX   NCBI_TaxID=402600 {ECO:0000313|EMBL:SER41346.1, ECO:0000313|Proteomes:UP000199352};
RN   [1] {ECO:0000313|Proteomes:UP000199352}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 4.3525 {ECO:0000313|Proteomes:UP000199352};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the IlvD/Edd family.
CC       {ECO:0000256|ARBA:ARBA00006486}.
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DR   EMBL; FOFR01000011; SER41346.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H9NZE3; -.
DR   STRING; 402600.SAMN05216188_11177; -.
DR   OrthoDB; 4744252at2; -.
DR   Proteomes; UP000199352; Unassembled WGS sequence.
DR   GO; GO:0016836; F:hydro-lyase activity; IEA:InterPro.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0019752; P:carboxylic acid metabolic process; IEA:UniProt.
DR   GO; GO:0044238; P:primary metabolic process; IEA:UniProt.
DR   Gene3D; 3.50.30.80; IlvD/EDD C-terminal domain-like; 1.
DR   InterPro; IPR042096; Dihydro-acid_dehy_C.
DR   InterPro; IPR000581; DiOHA_6PGluconate_deHydtase.
DR   InterPro; IPR020558; DiOHA_6PGluconate_deHydtase_CS.
DR   InterPro; IPR037237; IlvD/EDD_N.
DR   PANTHER; PTHR43183:SF2; DIHYDROXY-ACID DEHYDRATASE; 1.
DR   PANTHER; PTHR43183; HYPOTHETICAL DIHYDROXYACID DEHYDRATASE (EUROFUNG)-RELATED; 1.
DR   Pfam; PF00920; ILVD_EDD; 1.
DR   SUPFAM; SSF143975; IlvD/EDD N-terminal domain-like; 1.
DR   SUPFAM; SSF52016; LeuD/IlvD-like; 1.
DR   PROSITE; PS00886; ILVD_EDD_1; 1.
PE   3: Inferred from homology;
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Lyase {ECO:0000256|ARBA:ARBA00023239};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
SQ   SEQUENCE   571 AA;  61306 MW;  B74B6AF196100314 CRC64;
     MTGKGLRSAA WFEGEGLRAF SHNARMRQLG LNPAEHLGKP VIAILNTWSG INPCHMHLRE
     RAGQVERGVW AAGGHPLEFP VATLSETFQK PTPMLYRNLL SMETEELLRS YPVDGCVLMG
     GCDKTTPALL MGAASAGLPT IFVPAGPMLR GHWRGGKLAS GTDMWRYWDE KRAGTISDAD
     WAEIQSGLAR SPGTCMTMGT ASTMTAAAEA LGLTLPGASS IPAVDSAHHR MAAAAGTRIV
     EMVREGLAIG DVLSAEAYED AIRTVLALGG STNSYIHLIA MAGRSRIPLA LDDFDRLSRE
     VPVLASVQPA GEHLMEDFYY AGGLRGLLSR LRGSLHLDRI TVTGRTFGED LAGAEVHDPS
     VIRPVDDPIS AEGGLAVLRG NLAPGGAVIK YVAADPSLWR HTGPAVVFHG YRDLQARIND
     PDLEVTRDSV IVLAGSGPKG GPGMPEHGML PIPDKLLREG VRDLVRVSDA RMSGTSYGAC
     VLHVAPEAHV GGPLALVRDG DLVTLDVEAR VLRVEISDEE MRRRRAAWTP PPPTFERGYG
     ALYYEHITQA DQGCDFEFLS RPGRDPEPDA H
//