ID   A0A1H9P1M3_9CORY        Unreviewed;       653 AA.
AC   A0A1H9P1M3;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Putative drug exporter of the RND superfamily {ECO:0000313|EMBL:SER42090.1};
GN   ORFNames=SAMN05661109_00183 {ECO:0000313|EMBL:SER42090.1};
OS   Corynebacterium cystitidis DSM 20524.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC   Corynebacteriaceae; Corynebacterium.
OX   NCBI_TaxID=1121357 {ECO:0000313|EMBL:SER42090.1, ECO:0000313|Proteomes:UP000198929};
RN   [1] {ECO:0000313|EMBL:SER42090.1, ECO:0000313|Proteomes:UP000198929}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 20524 {ECO:0000313|EMBL:SER42090.1,
RC   ECO:0000313|Proteomes:UP000198929};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the resistance-nodulation-cell division (RND)
CC       (TC 2.A.6) family. MmpL subfamily. {ECO:0000256|ARBA:ARBA00010157}.
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DR   EMBL; FOGQ01000001; SER42090.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H9P1M3; -.
DR   STRING; 1121357.SAMN05661109_00183; -.
DR   Proteomes; UP000198929; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR004869; MMPL_dom.
DR   InterPro; IPR000731; SSD.
DR   PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR   PANTHER; PTHR33406:SF6; MEMBRANE PROTEIN SCO0839-RELATED; 1.
DR   Pfam; PF03176; MMPL; 2.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   PROSITE; PS50156; SSD; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        152..170
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        177..199
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        211..231
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        252..277
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        283..310
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        343..363
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        466..484
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        491..512
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        527..548
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        560..585
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        591..612
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          204..309
FT                   /note="SSD"
FT                   /evidence="ECO:0000259|PROSITE:PS50156"
FT   REGION          32..54
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   653 AA;  68745 MW;  F221B7BF4A14E087 CRC64;
     MTAQSVRLMR WVSLAIIAVT IVLIAIGPAQ SPSSPTAMLP DNSDSTAVAQ QRAQSSEDAG
     NAAVVLFTGV NPESFGQLQT KAEELGGPLI PNDEMDAAIV PVEVSSNSLL GNVDAVDDLR
     TTAAAGLPNG VQSQVTGPAA IDADLSGVFE GANFTLLAVT AIIVAALLII TYRSPVLWII
     PLLVIGFADR LVATTYTWVL DAAGMVWNES TGGILSVLVF GAGTNYALLL ISRYREELTN
     YDSRFESMAR AWAPTVRTIL ASAFTVVIGV LCLLASLTPT TRALGAAAAF GIVVAFLFSA
     FVLPGVLVLF GRWIFWPRRP NVGDTTTHRV FDAVGNQIAK RPITILTASL IFLGILCLGY
     FQITTGLTQS DQFIEKPESI TAAESLSDEF PATSATPAVI STSQPDAATA ALETAGFTVT
     DSDGFLQVSG GTTAEIRSSL SDVDAKVGGA DAELYDTEQA AKRDRVVVFP LVLGLVFIAL
     IFLLRSIVAP VIMVTSVLLT NIAALGLGWW VSSGLFGFER FDSTTPLYAF VFLVALGIDY
     TIFLVTRARE AAEREGTRHG ILSALSATGG VITSAGILLA AVFAALGVLP LVVLAQVGIV
     ICLGVLLDTL VVRSLVVPSI VQLLGEKFWW PARPDWPATA VADSGSTKLE EHL
//