ID   A0A1H9P5R4_9PSEU        Unreviewed;       278 AA.
AC   A0A1H9P5R4;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Spermine/spermidine synthase {ECO:0000313|EMBL:SER43586.1};
GN   ORFNames=SAMN05216188_111161 {ECO:0000313|EMBL:SER43586.1};
OS   Lentzea xinjiangensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Lentzea.
OX   NCBI_TaxID=402600 {ECO:0000313|EMBL:SER43586.1, ECO:0000313|Proteomes:UP000199352};
RN   [1] {ECO:0000313|Proteomes:UP000199352}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 4.3525 {ECO:0000313|Proteomes:UP000199352};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the spermidine/spermine synthase family.
CC       {ECO:0000256|ARBA:ARBA00007867}.
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DR   EMBL; FOFR01000011; SER43586.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H9P5R4; -.
DR   STRING; 402600.SAMN05216188_111161; -.
DR   OrthoDB; 8221452at2; -.
DR   Proteomes; UP000199352; Unassembled WGS sequence.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006596; P:polyamine biosynthetic process; IEA:UniProtKB-UniRule.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR030374; PABS.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   NCBIfam; NF037959; MFS_SpdSyn; 1.
DR   PANTHER; PTHR43317:SF9; POLYAMINE AMINOPROPYLTRANSFERASE 2; 1.
DR   PANTHER; PTHR43317; THERMOSPERMINE SYNTHASE ACAULIS5; 1.
DR   Pfam; PF01564; Spermine_synth; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR   PROSITE; PS51006; PABS_2; 1.
PE   3: Inferred from homology;
KW   Polyamine biosynthesis {ECO:0000256|ARBA:ARBA00023115, ECO:0000256|PROSITE-
KW   ProRule:PRU00354};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW   ProRule:PRU00354}.
FT   DOMAIN          1..227
FT                   /note="PABS"
FT                   /evidence="ECO:0000259|PROSITE:PS51006"
FT   ACT_SITE        143
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00354"
SQ   SEQUENCE   278 AA;  29562 MW;  D83CA580E1252676 CRC64;
     MGRQRPGTEA ITESIDSGVA ELVPDLGGRN SWTLRVNGTP QSHVDLDDPS YLEFEYVRRL
     GHIVDLTAPS RVLHLGGGAL TLARYVAELL PRASQQVAEI DAGLIAFIRR ELPPPPRVKI
     TTGDARAVLV KARPGSFDLI VSDCFAGART PAHLTSVEYV RQASAALADD GIYAANIGDG
     NGLQFARAQC ATVRAVFEHV CVLAEPGVFR GRRFGNFVIF ASHTGLPMQQ LTRATAGDPF
     PGRVEHGTGL TKFIGGTPVT TDETATLSPA PPSGLWGT
//