ID A0A1H9PGP0_9ACTN Unreviewed; 494 AA.
AC A0A1H9PGP0;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Chloride channel protein, CIC family {ECO:0000313|EMBL:SER47029.1};
GN ORFNames=SAMN05443377_1018 {ECO:0000313|EMBL:SER47029.1};
OS Propionibacterium cyclohexanicum.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Propionibacteriaceae; Propionibacterium.
OX NCBI_TaxID=64702 {ECO:0000313|EMBL:SER47029.1, ECO:0000313|Proteomes:UP000198815};
RN [1] {ECO:0000313|EMBL:SER47029.1, ECO:0000313|Proteomes:UP000198815}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 16859 {ECO:0000313|EMBL:SER47029.1,
RC ECO:0000313|Proteomes:UP000198815};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FOGZ01000001; SER47029.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H9PGP0; -.
DR STRING; 64702.SAMN05443377_1018; -.
DR OrthoDB; 9767361at2; -.
DR Proteomes; UP000198815; Unassembled WGS sequence.
DR GO; GO:0034707; C:chloride channel complex; IEA:UniProtKB-KW.
DR GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR CDD; cd00400; Voltage_gated_ClC; 1.
DR Gene3D; 1.10.3080.10; Clc chloride channel; 1.
DR InterPro; IPR014743; Cl-channel_core.
DR InterPro; IPR001807; Cl-channel_volt-gated.
DR PANTHER; PTHR43427; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR PANTHER; PTHR43427:SF6; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR Pfam; PF00654; Voltage_CLC; 1.
DR PRINTS; PR00762; CLCHANNEL.
DR SUPFAM; SSF81340; Clc chloride channel; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000198815};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 46..66
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 103..124
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 198..216
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 236..260
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 272..294
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 314..338
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 350..372
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 378..397
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 409..434
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 440..458
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 494 AA; 51314 MW; 9E20E325A84754F0 CRC64;
MSQPEPADPE DASEERSAHA PRRLRALAHR YTPHLPQSFQ DSINRWLLFG VVIGVVSGLG
AVIFYWCLSH ATQWLLVGIG GYQPPTTVGE GSGLPNGAFT RPWAIPLVVT GGALVAGILV
AWLAPEAEGH GTDAAIHAVH HDPTSLRGRV AVVKVIASSL VIGSGGSGGR EGPTAQISAT
VIAQLCRWLK VPRQDARIAV SAAMGSGIGA IFRAPMGGAL LGAELLYRED MESDALMPSF
VSSIVAFAVF GTFFGFRPIF GSHSAASFQH PVGLIWYACV GVAAGVAGRA YASIFYGGGA
LLKRLPVPNA IRPAIGGLCV GLIGLAVPAA LGTGYGWIQL EMTSDWLLTT PLWLVLVIPL
AKIVSTTLSI GSGGSGGVFG PGMVIGGCAG AAVWRLVHTL PGVTHDPMPY VIIGMIACFG
SVAHAPIGVM LMVAEMTGNL TLLAPAMLAM AIATLIVDGK SIYISQLRDR FEYYSLRERG
GSLGGHPLSP GPQP
//
