ID A0A1H9RJZ1_9ACTN Unreviewed; 314 AA.
AC A0A1H9RJZ1;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Chloramphenicol-sensitive protein RarD {ECO:0000313|EMBL:SER72363.1};
GN ORFNames=SAMN05443377_10791 {ECO:0000313|EMBL:SER72363.1};
OS Propionibacterium cyclohexanicum.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Propionibacteriaceae; Propionibacterium.
OX NCBI_TaxID=64702 {ECO:0000313|EMBL:SER72363.1, ECO:0000313|Proteomes:UP000198815};
RN [1] {ECO:0000313|EMBL:SER72363.1, ECO:0000313|Proteomes:UP000198815}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 16859 {ECO:0000313|EMBL:SER72363.1,
RC ECO:0000313|Proteomes:UP000198815};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the EamA transporter family.
CC {ECO:0000256|ARBA:ARBA00007362}.
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DR EMBL; FOGZ01000007; SER72363.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H9RJZ1; -.
DR STRING; 64702.SAMN05443377_10791; -.
DR OrthoDB; 369870at2; -.
DR Proteomes; UP000198815; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR InterPro; IPR000620; EamA_dom.
DR InterPro; IPR004626; RarD.
DR NCBIfam; TIGR00688; rarD; 1.
DR PANTHER; PTHR22911; ACYL-MALONYL CONDENSING ENZYME-RELATED; 1.
DR PANTHER; PTHR22911:SF137; PROTEIN RARD; 1.
DR Pfam; PF00892; EamA; 2.
DR SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 2.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000198815};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 9..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 39..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 72..92
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 104..121
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 128..145
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 151..167
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 179..200
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 212..233
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 245..262
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 268..289
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 9..144
FT /note="EamA"
FT /evidence="ECO:0000259|Pfam:PF00892"
FT DOMAIN 153..284
FT /note="EamA"
FT /evidence="ECO:0000259|Pfam:PF00892"
SQ SEQUENCE 314 AA; 34130 MW; 623ADC8D6F4BA3D3 CRC64;
MNEVEQRNGA VYGFAAYLIW GGFPLFFQLV RRSGAFEIIA YRIVFSLAFC LLLVALTRGW
RRIREILSNP RGLGLLALGG LLVMINWTVY VWGVNNGHTI DAALGYFINP LMSAVLGVSV
LGERLRRAQV VAFGIGALAV VVLVVGYGKV PWVALGVSTS FALYSLVKNR VGRRVDALSG
LVIETASVFP LAIAYLWWLG AAGGSTMGFA GGYGWLLVLS GPLTALPLLL FAAAASRVSL
TMIGILQYIC PMMQFCIGWL VFGERMPIKR WIGFALIWVA IAVFAADSAR RSTIGSVRRP
RIAGRRSQVS QARP
//
