ID A0A1H9RK81_9EURY Unreviewed; 1063 AA.
AC A0A1H9RK81;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=PAS domain S-box-containing protein {ECO:0000313|EMBL:SER73047.1};
GN ORFNames=SAMN04489841_4435 {ECO:0000313|EMBL:SER73047.1};
OS Natrinema salaciae.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC Natrialbaceae; Natrinema.
OX NCBI_TaxID=1186196 {ECO:0000313|EMBL:SER73047.1, ECO:0000313|Proteomes:UP000199114};
RN [1] {ECO:0000313|Proteomes:UP000199114}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 25055 {ECO:0000313|Proteomes:UP000199114};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00169}.
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DR EMBL; FOFD01000007; SER73047.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H9RK81; -.
DR STRING; 1186196.SAMN04489841_4435; -.
DR OrthoDB; 327291at2157; -.
DR Proteomes; UP000199114; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 3.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 2.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR NCBIfam; TIGR00229; sensory_box; 3.
DR PANTHER; PTHR43065:SF10; PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK3; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF13185; GAF_2; 2.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF13426; PAS_9; 2.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00086; PAC; 3.
DR SMART; SM00091; PAS; 3.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF55781; GAF domain-like; 2.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 3.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 3.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 8..120
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 148..219
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 427..497
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 502..553
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 711..784
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 841..1048
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT REGION 127..148
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1063 AA; 115846 MW; 3F359FA6A84C72F6 CRC64;
MGTNIGPNTT VVAVGSDTGG VVERALEERG VTTESVRTID ACLERLSNAD CVVVGSPSPD
GDPVDCCRRI RSHRSDVPVV VFPDDGSEAL AGAVVAAGAD GYVPRSQGVE TLTERLRALL
AERRTDGCAG DARPDATDSR AAASTDDHSD RLELLVEQSP LAIVEWSLEF EVQSWNPAAT
ELFGYTADEV IGESIVELLV LDEDRQAVRE YRNDLVDGET DGEPFRRVHR TVREDGTTVT
CEWFNAPLIE DGEVVSVLSF GQDVTADVKR ANALEALQET SQALLRAEST DEIADIVMAA
TEDVIDQPLA GIRFYDERTE TLELAGVTST LSEHADTVAS VGSGESVFWD AYAAQERTIV
ETVETERIPY DIAAEVGPTI FQPLGRHGLL TVASSGETAL DDAEINLIHV LAATAEAALD
RAARERELER TRTVVETVGD CVYQLDREGR FVTVNETMMA ETGYDRGDLL GEHVSRILTP
ESVERGARHI RSLTADNEQR VATYEITLIG ADGTRTPAEV SMSLLHSDGE LVGTVGIARD
ISDRKRMERK LVSRKGKIEG LHDVASRLDS CESHEEIYEE TVEAAEDVLN FDICCVDRAR
GKELVTQAIS SSLEADPDGT LGIDESIAGK TYRTGRSYRT GDVTTDDDAS PAVDGIRSVL
SVPIGDRGVF QAVSTEPDAF TIADEELAEL LLSHVTDALD RIDFEKRLRT ERDRFAALFE
NVPDAVVSVT QLADGPIVEA INPAFERIFG YDEAELVGTP VDETIVPPNR TANAETLNRQ
GSRGEIGTAE VKRRTADGLR DFRLRVVPIE TDGSSDRAFA LYTDITAQKQ RQKRLEILNR
VLRHDLRNGM NIINGCAEIL ADAVDGSDRQ YVETIRNRAS ELTGLAEKTR SVERVLDRDE
IPAGPIDLTT AVEQAVTRLE STHDVDVDCS LPDRAFARAD EYLQAALFQV LENAVEHNDR
SRPAIDVTLR DRPDDDVLTV TVADDGPGIP EEERELLEGD QEITQLRHAS GLGLWLVNWV
VTQAGGTLSF VDNEPRGTVV RLDIPRADME SVRSTSDGTA AGD
//
