ID   A0A1H9RYY3_9SPHI        Unreviewed;       596 AA.
AC   A0A1H9RYY3;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Chloride channel protein, CIC family {ECO:0000313|EMBL:SER77937.1};
GN   ORFNames=SAMN04488023_11642 {ECO:0000313|EMBL:SER77937.1};
OS   Pedobacter rhizosphaerae.
OC   Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC   Sphingobacteriaceae; Pedobacter.
OX   NCBI_TaxID=390241 {ECO:0000313|EMBL:SER77937.1, ECO:0000313|Proteomes:UP000199572};
RN   [1] {ECO:0000313|EMBL:SER77937.1, ECO:0000313|Proteomes:UP000199572}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 18610 {ECO:0000313|EMBL:SER77937.1,
RC   ECO:0000313|Proteomes:UP000199572};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; FOGG01000016; SER77937.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H9RYY3; -.
DR   STRING; 390241.SAMN04488023_11642; -.
DR   OrthoDB; 9812438at2; -.
DR   Proteomes; UP000199572; Unassembled WGS sequence.
DR   GO; GO:0034707; C:chloride channel complex; IEA:UniProtKB-KW.
DR   GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR   CDD; cd00400; Voltage_gated_ClC; 1.
DR   Gene3D; 3.10.580.10; CBS-domain; 1.
DR   Gene3D; 1.10.3080.10; Clc chloride channel; 1.
DR   InterPro; IPR000644; CBS_dom.
DR   InterPro; IPR046342; CBS_dom_sf.
DR   InterPro; IPR014743; Cl-channel_core.
DR   InterPro; IPR001807; Cl-channel_volt-gated.
DR   PANTHER; PTHR43427; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR   PANTHER; PTHR43427:SF6; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR   Pfam; PF00571; CBS; 1.
DR   Pfam; PF00654; Voltage_CLC; 1.
DR   PRINTS; PR00762; CLCHANNEL.
DR   SUPFAM; SSF54631; CBS-domain pair; 1.
DR   SUPFAM; SSF81340; Clc chloride channel; 1.
DR   PROSITE; PS51371; CBS; 1.
PE   4: Predicted;
KW   CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199572};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        25..45
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        65..83
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        160..187
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        199..217
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        229..252
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        272..290
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        322..346
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        352..371
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        383..406
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        412..429
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          534..594
FT                   /note="CBS"
FT                   /evidence="ECO:0000259|PROSITE:PS51371"
SQ   SEQUENCE   596 AA;  65974 MW;  83A659F0808E0FD2 CRC64;
     MYIRFVNYLD AVNQYRKSKV SNRNFLIILA VVVGILAGLA AAVLKSLTHH IEEFLQSDWH
     WKYKYYLYLF FPLIGIFLTV LYVKYFIRKS KFETGLTPLL YAISKKSSRV EPHNIYSQVI
     TAAVTVGFGG STGLEAPIVT SGSAIGSNLG RMLGLSYREI TMLVACGAAA GIAGAFNSPI
     AGIVFAIEIL LPEFTIPAFI PLLLSAATAA VVARLFYTQQ LFFLVTEGWK VNALAYYVVL
     ALLIGLFSIY FTKANYAIKG FFYKVKHPYA KVIVGGILLG GMVFLFPTLY GEGYITIKSL
     LRGDYLAVID NSIFADYNQI PALVILFTVV TIFAKSIATL VTLGAGGNGG TFAPSLIMGG
     LIGFIFSYTV NLSGIAQLNT ANFIVAGMAA ALSAIMHAPL TGIFLIAEIT GGYVLMVPLM
     ITSAISYAIN RGVQKHSIYT KALADKGELL SHEDKDTTVL NQMKLKYLIE KNHIQLRMND
     LLFLKMNEIL KSHKNICAVT DETGDFKGVI YVEELFREMM QIEERENITA QHLVQPAPAI
     VYENEDLKLV LQKMEQNNVW LLPVVTDQNI YKGFISKTAV FNKYRALLMR QADYMN
//