ID   A0A1H9SI96_9CORY        Unreviewed;       472 AA.
AC   A0A1H9SI96;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   SubName: Full=Alanine or glycine:cation symporter, AGCS family {ECO:0000313|EMBL:SER83959.1};
GN   ORFNames=SAMN05661109_01105 {ECO:0000313|EMBL:SER83959.1};
OS   Corynebacterium cystitidis DSM 20524.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC   Corynebacteriaceae; Corynebacterium.
OX   NCBI_TaxID=1121357 {ECO:0000313|EMBL:SER83959.1, ECO:0000313|Proteomes:UP000198929};
RN   [1] {ECO:0000313|EMBL:SER83959.1, ECO:0000313|Proteomes:UP000198929}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 20524 {ECO:0000313|EMBL:SER83959.1,
RC   ECO:0000313|Proteomes:UP000198929};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363064};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU363064}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the alanine or glycine:cation symporter (AGCS)
CC       (TC 2.A.25) family. {ECO:0000256|ARBA:ARBA00009261,
CC       ECO:0000256|RuleBase:RU363064}.
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DR   EMBL; FOGQ01000004; SER83959.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H9SI96; -.
DR   STRING; 1121357.SAMN05661109_01105; -.
DR   Proteomes; UP000198929; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005283; F:amino acid:sodium symporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR   InterPro; IPR001463; Na/Ala_symport.
DR   NCBIfam; TIGR00835; agcS; 1.
DR   PANTHER; PTHR30330; AGSS FAMILY TRANSPORTER, SODIUM-ALANINE; 1.
DR   PANTHER; PTHR30330:SF3; TRANSCRIPTIONAL REGULATOR, LRP FAMILY-RELATED; 1.
DR   Pfam; PF01235; Na_Ala_symp; 1.
DR   PRINTS; PR00175; NAALASMPORT.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|RuleBase:RU363064};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363064};
KW   Symport {ECO:0000256|RuleBase:RU363064};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU363064};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU363064};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363064}.
FT   TRANSMEM        20..40
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        150..168
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        188..209
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        216..236
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        242..269
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        311..331
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        351..376
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        396..416
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        422..440
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
SQ   SEQUENCE   472 AA;  49689 MW;  88E178CD2373ABB4 CRC64;
     MLDSLNTALS AASSFVWGPW LLIPVLLGTG IFLTFRLAGI QFRTLGRSLR HALIDQQEDG
     EGDISNYQAL TTALAATVGT GNIVGVATAI ALGGPGALFW IWVTGAVGMA SKYTEAYLGV
     RFRVTDAKGA QSGGPQEYLR RGIPGPVGQI LAFLFTVFAI IASFGIGNLT QGNSVAAGME
     DTFGVDPWIT GIIMFVAVGA VLLGGIQAIG KITSAFVPLM IFVYVTGGIV SLVLMADQIP
     AALGAIFTDA FTGTAATGGF LGAGIMMAVR FGVARGIFSN ESGMGSAAIA AAAAKTSHPT
     RQALVSMTQT FIDTMIVVTI TGLVIVTSGV WDQGADNAAT MTSSAFSTVL GSQWGGTIVS
     VSLIFFAFST IIGWSYYGER SIVALLGQWA SLPYRLFFTC VVFIGAISQI EIAWTFSDLA
     NGLMALPNLI GLLILSGLVA RETREYLKFD PHLKRSPEEV AEFVKKQQMH WK
//