ID A0A1H9T4C1_9MICO Unreviewed; 311 AA.
AC A0A1H9T4C1;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE SubName: Full=Threonine/homoserine efflux transporter RhtA {ECO:0000313|EMBL:SER92072.1};
GN ORFNames=SAMN05216199_1438 {ECO:0000313|EMBL:SER92072.1};
OS Pedococcus cremeus.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Intrasporangiaceae;
OC Pedococcus.
OX NCBI_TaxID=587636 {ECO:0000313|EMBL:SER92072.1, ECO:0000313|Proteomes:UP000199019};
RN [1] {ECO:0000313|Proteomes:UP000199019}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 1.6963 {ECO:0000313|Proteomes:UP000199019};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FOHB01000002; SER92072.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H9T4C1; -.
DR STRING; 587636.SAMN05216199_1438; -.
DR OrthoDB; 3182968at2; -.
DR Proteomes; UP000199019; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.10.3730.20; -; 1.
DR InterPro; IPR000620; EamA_dom.
DR PANTHER; PTHR42920:SF5; EAMA DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR42920; OS03G0707200 PROTEIN-RELATED; 1.
DR Pfam; PF00892; EamA; 2.
DR SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 2.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000199019};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 45..63
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 75..91
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 103..123
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 130..151
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 157..176
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 183..202
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 214..232
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 244..262
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 268..286
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 17..146
FT /note="EamA"
FT /evidence="ECO:0000259|Pfam:PF00892"
FT DOMAIN 154..286
FT /note="EamA"
FT /evidence="ECO:0000259|Pfam:PF00892"
SQ SEQUENCE 311 AA; 32455 MW; 38118E327F75D303 CRC64;
MTARPAARSS ARSARLATLL LMGVTAVWGS TFFLIRDLVV HVPSADFLAV RFAIAAVVMF
AVFRRQTLAL SRADLLTGIG LGVLYGAAQL LQTTGLEHTD ASVSGFVTGT YVVLTPVFGA
LIFRDRIAPS TWVAVGLATA GLAVLSLRGL AVGYGEALTL ASAALYALHI IGLGRFSRAH
TATGLATVQA FVIALMCSVA AVPDGLTLPS DGGQWASLLY MALVAGAVAL WAQTWAQSHL
PATRAAIVMT LEPVFAAFFA VLAGGERLTA RMLGGGALVL TAMYVVELLG RRTPETTAEQ
DPPAELLHHE V
//
