ID   A0A1H9TIP3_9SPHI        Unreviewed;       385 AA.
AC   A0A1H9TIP3;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=Alcohol dehydrogenase {ECO:0000313|EMBL:SER97031.1};
GN   ORFNames=SAMN04488023_12317 {ECO:0000313|EMBL:SER97031.1};
OS   Pedobacter rhizosphaerae.
OC   Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC   Sphingobacteriaceae; Pedobacter.
OX   NCBI_TaxID=390241 {ECO:0000313|EMBL:SER97031.1, ECO:0000313|Proteomes:UP000199572};
RN   [1] {ECO:0000313|EMBL:SER97031.1, ECO:0000313|Proteomes:UP000199572}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 18610 {ECO:0000313|EMBL:SER97031.1,
RC   ECO:0000313|Proteomes:UP000199572};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947,
CC         ECO:0000256|RuleBase:RU361277};
CC   -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC       family. {ECO:0000256|RuleBase:RU361277}.
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DR   EMBL; FOGG01000023; SER97031.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H9TIP3; -.
DR   STRING; 390241.SAMN04488023_12317; -.
DR   OrthoDB; 9787435at2; -.
DR   Proteomes; UP000199572; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd08283; FDH_like_1; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR002328; ADH_Zn_CS.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   PANTHER; PTHR42813:SF2; DEHYDROGENASE, ZINC-CONTAINING, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G02810)-RELATED; 1.
DR   PANTHER; PTHR42813; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS00059; ADH_ZINC; 1.
PE   3: Inferred from homology;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW   ECO:0000256|RuleBase:RU361277};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199572};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU361277}.
FT   DOMAIN          10..383
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
SQ   SEQUENCE   385 AA;  41909 MW;  5660C68BA7AA285C CRC64;
     MKAAVFHKPG DIRVDTVPDP KILDPRDIIL KVTSTAICGS DLHILSGAVP QKDPMVMGHE
     FMGIVEEVGS AITNLKVGDR VVVPFPISCG KCFFCTHEAS PACEDSNYKN YGPAGNVADQ
     KGGALFGYTD LYGGYSGGQA QYVRVPYADI SPRVVPEHLS DEQALFLTDI FPTGWSAIDW
     AQLKGGETVA IFGSGPVGLM AQKAAWINGA ARVIAIDPLD YRLERARTAN NVETLNPHKV
     DVVEAIREMT GGRGADVCVD AVGFEPERSL IDKLKATIHF EKGSMKVLEM CFESVRRMGT
     VSIMGVYGSP YDNFPLFRMF DKGITIKQGQ APVLNYIDKL IALVSEGKVV LDDIITHTLP
     LEDAAHAYKI FDEKQEDCVK VVLKP
//