ID A0A1H9TN93_9MICO Unreviewed; 769 AA.
AC A0A1H9TN93;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=Cu+-exporting ATPase {ECO:0000313|EMBL:SER98528.1};
GN ORFNames=SAMN05216199_1683 {ECO:0000313|EMBL:SER98528.1};
OS Pedococcus cremeus.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Intrasporangiaceae;
OC Pedococcus.
OX NCBI_TaxID=587636 {ECO:0000313|EMBL:SER98528.1, ECO:0000313|Proteomes:UP000199019};
RN [1] {ECO:0000313|Proteomes:UP000199019}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 1.6963 {ECO:0000313|Proteomes:UP000199019};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
CC -!- SIMILARITY: Belongs to the cation transport ATPase (P-type) (TC 3.A.3)
CC family. Type IB subfamily. {ECO:0000256|ARBA:ARBA00006024,
CC ECO:0000256|RuleBase:RU362081}.
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DR EMBL; FOHB01000002; SER98528.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H9TN93; -.
DR STRING; 587636.SAMN05216199_1683; -.
DR OrthoDB; 7059309at2; -.
DR Proteomes; UP000199019; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0019829; F:ATPase-coupled monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd00371; HMA; 1.
DR CDD; cd02094; P-type_ATPase_Cu-like; 1.
DR Gene3D; 3.30.70.100; -; 1.
DR Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 1.
DR Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR InterPro; IPR018303; ATPase_P-typ_P_site.
DR InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR017969; Heavy-metal-associated_CS.
DR InterPro; IPR006121; HMA_dom.
DR InterPro; IPR036163; HMA_dom_sf.
DR InterPro; IPR027256; P-typ_ATPase_IB.
DR InterPro; IPR001757; P_typ_ATPase.
DR InterPro; IPR044492; P_typ_ATPase_HD_dom.
DR NCBIfam; TIGR01511; ATPase-IB1_Cu; 1.
DR NCBIfam; TIGR01525; ATPase-IB_hvy; 1.
DR NCBIfam; TIGR01494; ATPase_P-type; 2.
DR PANTHER; PTHR43520; ATP7, ISOFORM B; 1.
DR PANTHER; PTHR43520:SF8; COPPER-TRANSPORTING ATPASE 2; 1.
DR Pfam; PF00122; E1-E2_ATPase; 1.
DR Pfam; PF00403; HMA; 1.
DR Pfam; PF00702; Hydrolase; 1.
DR PRINTS; PR00119; CATATPASE.
DR PRINTS; PR00120; HATPASE.
DR SFLD; SFLDG00002; C1.7:_P-type_atpase_like; 1.
DR SFLD; SFLDF00027; p-type_atpase; 1.
DR SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 1.
DR SUPFAM; SSF81665; Calcium ATPase, transmembrane domain M; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR SUPFAM; SSF55008; HMA, heavy metal-associated domain; 1.
DR PROSITE; PS00154; ATPASE_E1_E2; 1.
DR PROSITE; PS01229; COF_2; 1.
DR PROSITE; PS01047; HMA_1; 1.
DR PROSITE; PS50846; HMA_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU362081};
KW Cell membrane {ECO:0000256|RuleBase:RU362081};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362081};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU362081};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU362081};
KW Reference proteome {ECO:0000313|Proteomes:UP000199019};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362081};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362081}.
FT TRANSMEM 114..134
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 140..162
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 174..194
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 214..236
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 374..396
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 402..429
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 720..736
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 742..760
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT DOMAIN 12..76
FT /note="HMA"
FT /evidence="ECO:0000259|PROSITE:PS50846"
FT REGION 74..103
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 769 AA; 78549 MW; F8939D56FE539086 CRC64;
MTTPVEHLGN TRSLDLEIGG MTCASCAARI EKKLNKMPGV TASVNYATEK AHVQVSEDVA
AEDLVATVEA TGYTATLPAP PPSPDQPGTG VTGPPADAGQ QAKDAEAAAW RQRLVVSAVL
TVPVLLMAMV PALQFDNWQW VSLTLASPVV VWGALPFHRA AWTNLRHGAA TMDTLISVGV
GAAYLWSLWA LLFTDAGTTG MRMPFELLPS RSEGAANIYL EVAAAVTTFI VAGRYFEARA
KRTSGAALRA LLDMGAKDVA VLRDGPAGPV ESRVAIGQLQ VGDQFVVRPG EKVATDGTVV
SGTSAVDASM LTGESVPVEV GPGDAVVGAT VNAGGRLVVR ATRVGADTQL AQMARLVEEA
QSGKAEVQRL ADRVSAVFVP IVIGLALATL AAWLLTGHAP TAAFTAAVAV LIIACPCALG
LATPTALLVG TGRGAQLGIL IKGPQVLEST RRVDTVVLDK TGTVTTGHMG VLGVHPAPGE
SLSEVLAVGG SLENASEHPI GRAIAQHAAA SGATLADVDG FTAHGGSGVS GVVGGHAAMA
GRRRWLAEQW SLTAPAALVA VADDAEALGQ TPVWVGWDGA VRAVVVVADT VKDSSAAAIA
ELRSLGLRPV LLTGDNARAA RAVAAQVGIG PDDVIAEVLP ADKVDAVKRL QDEGATVAMV
GDGVNDAAAL AQADLGLAMG TGTDVAIEAS DLTLVSGDLR AAPDAIRLAR ATLRTIKGNL
FWAFAYNVAA LPLAALGLLN PLIAGAAMAF SSVFVVSNSL RLRRFDPSR
//
