ID A0A1H9TY03_9MICO Unreviewed; 365 AA.
AC A0A1H9TY03;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=B12 binding domain-containing protein {ECO:0000313|EMBL:SES02125.1};
GN ORFNames=SAMN05216199_1819 {ECO:0000313|EMBL:SES02125.1};
OS Pedococcus cremeus.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Intrasporangiaceae;
OC Pedococcus.
OX NCBI_TaxID=587636 {ECO:0000313|EMBL:SES02125.1, ECO:0000313|Proteomes:UP000199019};
RN [1] {ECO:0000313|Proteomes:UP000199019}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 1.6963 {ECO:0000313|Proteomes:UP000199019};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FOHB01000002; SES02125.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H9TY03; -.
DR STRING; 587636.SAMN05216199_1819; -.
DR OrthoDB; 9800334at2; -.
DR Proteomes; UP000199019; Unassembled WGS sequence.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd01104; HTH_MlrA-CarA; 1.
DR Gene3D; 1.10.1660.10; -; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR Gene3D; 1.10.1240.10; Methionine synthase domain; 1.
DR InterPro; IPR003759; Cbl-bd_cap.
DR InterPro; IPR036724; Cobalamin-bd_sf.
DR InterPro; IPR009061; DNA-bd_dom_put_sf.
DR InterPro; IPR000551; MerR-type_HTH_dom.
DR InterPro; IPR047057; MerR_fam.
DR InterPro; IPR036594; Meth_synthase_dom.
DR PANTHER; PTHR30204:SF96; MERR FAMILY REGULATORY PROTEIN; 1.
DR PANTHER; PTHR30204; REDOX-CYCLING DRUG-SENSING TRANSCRIPTIONAL ACTIVATOR SOXR; 1.
DR Pfam; PF02607; B12-binding_2; 1.
DR Pfam; PF13411; MerR_1; 1.
DR SMART; SM00422; HTH_MERR; 1.
DR SUPFAM; SSF52242; Cobalamin (vitamin B12)-binding domain; 1.
DR SUPFAM; SSF46955; Putative DNA-binding domain; 1.
DR PROSITE; PS50937; HTH_MERR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000199019}.
FT DOMAIN 63..132
FT /note="HTH merR-type"
FT /evidence="ECO:0000259|PROSITE:PS50937"
FT REGION 1..38
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..16
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 365 AA; 38552 MW; EE2CE0EFC57F4F2D CRC64;
MDTKDRSGDR TDTTREALGA TEASTAAHQE EGVRTTEGVR ATRAETTADG QNPELHVPRV
ALTWSVGGVA ERLDLAPSTL RTWDRRYGIG PSQRTEGGHR RYDEVDIQRV RLMAQLTGRG
VPAGTAARVA TSVDAAGLAS ALAPNTPTAA GGHPGAHSAV EAIVSSAAAL DADGLARIYQ
RVTRESDLVS AWTSVLAPAL RKIGERWSDG SLGVDSEHLA SELLVTELRS LTRANRARIG
GRREVVLASA DEEQHYLPLV AVEAELSLQG IGCLFLGPRV PAEALIDLVG RSTPPVVFLW
ASITRPATDP LWTALSSIER PLTLVIGGPG WPEDLTPTSP TVTLRRAATL DQACEALSTA
VLPAG
//
