ID A0A1H9V2E3_9BACI Unreviewed; 295 AA.
AC A0A1H9V2E3;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=23S rRNA (Guanine745-N1)-methyltransferase {ECO:0000313|EMBL:SES15417.1};
GN ORFNames=SAMN05518684_10969 {ECO:0000313|EMBL:SES15417.1};
OS Salipaludibacillus aurantiacus.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae.
OX NCBI_TaxID=1601833 {ECO:0000313|EMBL:SES15417.1, ECO:0000313|Proteomes:UP000198571};
RN [1] {ECO:0000313|EMBL:SES15417.1, ECO:0000313|Proteomes:UP000198571}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S9 {ECO:0000313|EMBL:SES15417.1,
RC ECO:0000313|Proteomes:UP000198571};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FOGT01000009; SES15417.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1H9V2E3; -.
DR STRING; 1601833.SAMN05518684_10969; -.
DR OrthoDB; 5522265at2; -.
DR Proteomes; UP000198571; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR041698; Methyltransf_25.
DR InterPro; IPR048647; RlmA_N.
DR InterPro; IPR016718; rRNA_m1G-MeTrfase_A_prd.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR43460:SF1; METHYLTRANSF_11 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43460; METHYLTRANSFERASE; 1.
DR Pfam; PF13649; Methyltransf_25; 1.
DR Pfam; PF21302; RlmA_N; 1.
DR PIRSF; PIRSF018249; MyrA_prd; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PIRSR:PIRSR018249-1};
KW Methyltransferase {ECO:0000313|EMBL:SES15417.1};
KW S-adenosyl-L-methionine {ECO:0000256|PIRSR:PIRSR018249-2};
KW Transferase {ECO:0000313|EMBL:SES15417.1};
KW Zinc {ECO:0000256|PIRSR:PIRSR018249-1}.
FT DOMAIN 21..62
FT /note="23S rRNA (guanine(745)-N(1))-methyltransferase N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF21302"
FT DOMAIN 106..193
FT /note="Methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF13649"
FT BINDING 23
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PIRSR:PIRSR018249-1"
FT BINDING 26
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PIRSR:PIRSR018249-1"
FT BINDING 40
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PIRSR:PIRSR018249-1"
FT BINDING 44
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000256|PIRSR:PIRSR018249-1"
FT BINDING 83
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PIRSR:PIRSR018249-2"
FT BINDING 112..113
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PIRSR:PIRSR018249-2"
FT BINDING 204
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000256|PIRSR:PIRSR018249-2"
SQ SEQUENCE 295 AA; 33658 MW; 74322FDEA07BD415 CRC64;
MNKVTKRRRR TDYARYFEDV FKCPVCGEDM KVTDSCQLVC NRNHSFDFAK QGYVNLLPKH
VKTKYTKDLF EARKSLMTEE SFFKPVTDKI AGIIGKYGFG EKVNLLDMGC GEGSHLTAVR
KAVKEASGAE IMGAGVDLAK EGILEAAKQE DDLLWAVSDL ANTPFKAGKF DVLLNILSPS
NYEEFKRLMK NGGLVIKVVP GENYLKELRY ALFEEKHKHS YSNTDTIDRF TEHFTVVERW
PVSYTVNLTN RAVSWLVKMT PLAWEACEDR IKAFLKHEEI SMTVDTEIIV GRKKE
//
