ID   A0A1H9VIP0_9PSEU        Unreviewed;       621 AA.
AC   A0A1H9VIP0;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   SubName: Full=Glucosylceramidase {ECO:0000313|EMBL:SES21438.1};
GN   ORFNames=SAMN05216188_12690 {ECO:0000313|EMBL:SES21438.1};
OS   Lentzea xinjiangensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Lentzea.
OX   NCBI_TaxID=402600 {ECO:0000313|EMBL:SES21438.1, ECO:0000313|Proteomes:UP000199352};
RN   [1] {ECO:0000313|Proteomes:UP000199352}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 4.3525 {ECO:0000313|Proteomes:UP000199352};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 30 family.
CC       {ECO:0000256|ARBA:ARBA00005382, ECO:0000256|RuleBase:RU361188}.
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DR   EMBL; FOFR01000026; SES21438.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H9VIP0; -.
DR   STRING; 402600.SAMN05216188_12690; -.
DR   OrthoDB; 9806701at2; -.
DR   Proteomes; UP000199352; Unassembled WGS sequence.
DR   GO; GO:0004348; F:glucosylceramidase activity; IEA:InterPro.
DR   GO; GO:0006665; P:sphingolipid metabolic process; IEA:InterPro.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR   InterPro; IPR000421; FA58C.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR033452; GH30_C.
DR   InterPro; IPR001139; Glyco_hydro_30.
DR   InterPro; IPR033453; Glyco_hydro_30_TIM-barrel.
DR   InterPro; IPR013780; Glyco_hydro_b.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR11069; GLUCOSYLCERAMIDASE; 1.
DR   PANTHER; PTHR11069:SF23; LYSOSOMAL ACID GLUCOSYLCERAMIDASE; 1.
DR   Pfam; PF00754; F5_F8_type_C; 1.
DR   Pfam; PF02055; Glyco_hydro_30; 1.
DR   Pfam; PF17189; Glyco_hydro_30C; 1.
DR   PRINTS; PR00843; GLHYDRLASE30.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR   PROSITE; PS50022; FA58C_3; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|RuleBase:RU361188};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361188};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           22..621
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5011577232"
FT   DOMAIN          479..621
FT                   /note="F5/8 type C"
FT                   /evidence="ECO:0000259|PROSITE:PS50022"
SQ   SEQUENCE   621 AA;  67466 MW;  62291C2CA6C40D1D CRC64;
     MRTTAIVALV LGLTAVPAAD AATKPHGPQV RVWVTTPDRA ELLHEREPIA FGTKASAHPT
     IVVDPDRRYQ EVDGFGASIT DSSAEVLAGL APAVRAGTLR KLFDPVHGIG VSFLRQPVGS
     SDFTAAEEHY TYDDVPAGQT DFALRHFSVR HDEAKILPLL REAKRLNPRL KVMATPWSPP
     AWMKTNDSLV GGQLKDDPRI YDAYARYLVK FVQAYTRAGV PIDFLSVQNE PQNRKPDAYP
     GTDMPVAQQL KVIEALGPRL KAASPRTRIL GYDHNWATHP NDGDVETDYP FQVLRDRAAR
     WIAGTAFHCY YGDPSAQTAL HDAFPDKGIW FTECSGSKGA TDPPAKVFGD TLRWHARNVV
     LGTTRNWARS AVNWNIALDS TGGPHLGGCG TCTGLVTAQP DGSVRTDAEY YTIGHLSKFV
     KPGARRIAST SFGTTGWNGQ IMDAAFRNPD GSTALVVHNQ NDDPRTFAVN LGERTFEHTL
     PGGALATFTW TTRHRDGLDL VPLTGATASP GGAPAIDDDA STRWSSGAPQ AAGHHLLVDL
     GRREEFRRVA VDSGGYLGDH VRNWALSVSD DGEGWRTVAS GAGTGQLTTI DIRRTSARYV
     RITSTGAASN WWSIADFRLY N
//