ID   A0A1H9W020_9BACI        Unreviewed;       234 AA.
AC   A0A1H9W020;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   RecName: Full=pre-crRNA processing endonuclease {ECO:0000256|PIRNR:PIRNR029950};
DE            EC=3.1.-.- {ECO:0000256|PIRNR:PIRNR029950};
GN   ORFNames=SAMN04487944_13113 {ECO:0000313|EMBL:SES27285.1};
OS   Gracilibacillus ureilyticus.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Gracilibacillus.
OX   NCBI_TaxID=531814 {ECO:0000313|EMBL:SES27285.1, ECO:0000313|Proteomes:UP000199687};
RN   [1] {ECO:0000313|EMBL:SES27285.1, ECO:0000313|Proteomes:UP000199687}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 1.7727 {ECO:0000313|EMBL:SES27285.1,
RC   ECO:0000313|Proteomes:UP000199687};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: CRISPR (clustered regularly interspaced short palindromic
CC       repeat) is an adaptive immune system that provides protection against
CC       mobile genetic elements (viruses, transposable elements and conjugative
CC       plasmids). CRISPR clusters contain spacers, sequences complementary to
CC       antecedent mobile elements, and target invading nucleic acids. CRISPR
CC       clusters are transcribed and processed into CRISPR RNA (crRNA).
CC       {ECO:0000256|PIRNR:PIRNR029950}.
CC   -!- SIMILARITY: Belongs to the CRISPR-associated protein Cas5 family.
CC       Subtype I-C/Dvulg subfamily. {ECO:0000256|PIRNR:PIRNR029950}.
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DR   EMBL; FOGL01000031; SES27285.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H9W020; -.
DR   STRING; 531814.SAMN04487944_13113; -.
DR   OrthoDB; 5621871at2; -.
DR   Proteomes; UP000199687; Unassembled WGS sequence.
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-UniRule.
DR   GO; GO:0043571; P:maintenance of CRISPR repeat elements; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.70.2660; -; 1.
DR   InterPro; IPR021124; CRISPR-assoc_prot_Cas5.
DR   InterPro; IPR013422; CRISPR-assoc_prot_Cas5_N.
DR   InterPro; IPR010155; CRISPR-assoc_prot_Cas5d.
DR   NCBIfam; TIGR01876; cas_Cas5d; 1.
DR   NCBIfam; TIGR02593; CRISPR_cas5; 1.
DR   Pfam; PF09704; Cas_Cas5d; 1.
DR   PIRSF; PIRSF029950; Cas_CT1134; 1.
PE   3: Inferred from homology;
KW   Antiviral defense {ECO:0000256|ARBA:ARBA00023118,
KW   ECO:0000256|PIRNR:PIRNR029950};
KW   Endonuclease {ECO:0000256|PIRNR:PIRNR029950};
KW   Hydrolase {ECO:0000256|PIRNR:PIRNR029950};
KW   Nuclease {ECO:0000256|PIRNR:PIRNR029950};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199687};
KW   RNA-binding {ECO:0000256|PIRNR:PIRNR029950}.
SQ   SEQUENCE   234 AA;  27436 MW;  F5BD578DE4AAD62D CRC64;
     MRNGIEFELT GKYALFTDPL TKIGGEKSTY QIPTYQSLKG IVESIYWKPS IIIYVDELRI
     INPIQMESKG IRPIEYSGGN TLAYYTYLKD VRYRVKAHFE FNPYRPELAA DHNEHKHHNI
     MMRALKAGGR RDIYLGTREC QGYVEPCDFH GGNGFYDEID ELRFEPMVHG FNYPDETGKD
     ELEVRLWRPV MNNGVIQFPK PNEIEQVRTI KQMKTKQFDH TNVQFVEDTL NEIE
//