ID   A0A1H9WP64_9ACTN        Unreviewed;       378 AA.
AC   A0A1H9WP64;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   SubName: Full=Geranylgeranyl diphosphate synthase, type I {ECO:0000313|EMBL:SES35223.1};
GN   ORFNames=SAMN04487983_104460 {ECO:0000313|EMBL:SES35223.1};
OS   Streptomyces sp. yr375.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1761906 {ECO:0000313|EMBL:SES35223.1, ECO:0000313|Proteomes:UP000198568};
RN   [1] {ECO:0000313|EMBL:SES35223.1, ECO:0000313|Proteomes:UP000198568}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YR375 {ECO:0000313|EMBL:SES35223.1,
RC   ECO:0000313|Proteomes:UP000198568};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|ARBA:ARBA00001946};
CC   -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC       {ECO:0000256|RuleBase:RU004466}.
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DR   EMBL; FOFF01000044; SES35223.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H9WP64; -.
DR   STRING; 1761906.SAMN04487983_104460; -.
DR   OrthoDB; 4497239at2; -.
DR   Proteomes; UP000198568; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR   Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR   InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR   InterPro; IPR000092; Polyprenyl_synt.
DR   InterPro; IPR033749; Polyprenyl_synt_CS.
DR   PANTHER; PTHR43281; FARNESYL DIPHOSPHATE SYNTHASE; 1.
DR   PANTHER; PTHR43281:SF1; FARNESYL DIPHOSPHATE SYNTHASE; 1.
DR   Pfam; PF00348; polyprenyl_synt; 1.
DR   SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR   SUPFAM; SSF48576; Terpenoid synthases; 1.
DR   PROSITE; PS00723; POLYPRENYL_SYNTHASE_1; 1.
PE   3: Inferred from homology;
KW   Isoprene biosynthesis {ECO:0000256|ARBA:ARBA00023229};
KW   Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198568};
KW   Transferase {ECO:0000256|RuleBase:RU004466}.
SQ   SEQUENCE   378 AA;  41060 MW;  B9674C004CADD843 CRC64;
     MPHTAAGPVT AGPGERLRER IAGYERRFRT LFEEYFDALA AGALDAPSFS RFTPECLALL
     RDLSLRGGKR MRVVLLNEAA RLVTDEPVAG LDSAALSIEL LQTHGLVHDD LIDDSATRRG
     GPSTYYAYRE KFPHDRQAAI GLTVLAGDLA LALSLRALLD APLPLALRQA MVEVQTRAAT
     DTFVGQIVDL ERDFTPAVPD EDVLHGVADY KSARYSLLAP LRLGLLAAGA QPADYDDELR
     RYAQLVGICG QMRDDYLDLF GDTATLGKPT GTDLRDGKRS YTVAALLSAV ADSGSSGNSG
     SDRAVVESAL GDASGTPETV AAVREIAERL GVPDRLRADM RRHAEQASRV AAAWRPRWRD
     EAVTFFEQLP GWSIERTR
//