ID   A0A1H9WUH0_9RHOB        Unreviewed;       659 AA.
AC   A0A1H9WUH0;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   SubName: Full=Na+/H+ antiporter NhaC {ECO:0000313|EMBL:SES37588.1};
GN   ORFNames=SAMN04490244_11368 {ECO:0000313|EMBL:SES37588.1};
OS   Tranquillimonas rosea.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Roseobacteraceae; Tranquillimonas.
OX   NCBI_TaxID=641238 {ECO:0000313|EMBL:SES37588.1, ECO:0000313|Proteomes:UP000198885};
RN   [1] {ECO:0000313|EMBL:SES37588.1, ECO:0000313|Proteomes:UP000198885}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 23042 {ECO:0000313|EMBL:SES37588.1,
RC   ECO:0000313|Proteomes:UP000198885};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; FOGU01000013; SES37588.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H9WUH0; -.
DR   STRING; 641238.SAMN04490244_11368; -.
DR   OrthoDB; 9762978at2; -.
DR   Proteomes; UP000198885; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR018461; Na/H_Antiport_NhaC-like_C.
DR   PANTHER; PTHR43478; NA+/H+ ANTIPORTER-RELATED; 1.
DR   PANTHER; PTHR43478:SF1; NA_H_ANTIPORTER DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF03553; Na_H_antiporter; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198885};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           24..659
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5011525997"
FT   TRANSMEM        121..140
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        147..170
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        190..212
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        233..252
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        272..294
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        315..338
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        387..407
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        427..448
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        454..477
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        489..516
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        522..540
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        619..639
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          288..613
FT                   /note="Na+/H+ antiporter NhaC-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF03553"
FT   REGION          357..376
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   659 AA;  69656 MW;  C2EEB3992D3F6674 CRC64;
     MRPLRLLILV ASLWSIAVSA ALAQDDRAPR QITFEPPRVV LTGIAFDQTI TAAARPEGPL
     TLTVAGESYE IAPDAFSPPD DSEAVTLQAT VSDVTVGQGG DFSMVLSRGD ETLAEGQSTT
     LPAWLSILPA LLAIGAALVT RQVIPSLFLG IALGSWFTYG LSISGIWFGL LDVIQIYVLE
     ALVPPNGAKS HMQIVIFTLM MGGMIGIIYR NGGAHAIAAR IASMAKTRRR TQLGSCGLGF
     AIFFSTYANS LIVGNTMRPV TDRMRISREK LAYIVDSTAA PLASIAIIST WIGYQLGLIE
     EAMGEISHSE SAYSIFLNAL PYNFYPIFAL AMVIMVGATG RDFGPMAKAE RRALETGQVI
     RKDGQTEDDE EEGGDELTLK EGVPQRSINA ILPIGLLIVM VAAGIYVTGD GDSIRAIMGS
     ADGNTALVWA ALVSVILAAA MSIGQRILTV NETMAAWFAG LRSVLFVMII LTLAWALSAI
     AEDLHTASFL VSILGDTIAP AWLPALLFVL SAAVSFAVGT SWGTMGILMP LAVPLIWALM
     QNAGLSIEED GHILYATIGT ILAGSVWGDH CSPISDTTII SSVASGSDHI DHVRTQIPYA
     LTVGAVALAL GLVPTGYGVP WYLTLPAGIA VLFGVVMIVG RPMAERAETD KVADPQPAE
//