ID   A0A1H9WYM5_9PSEU        Unreviewed;       792 AA.
AC   A0A1H9WYM5;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   SubName: Full=Caspase domain-containing protein {ECO:0000313|EMBL:SES39058.1};
GN   ORFNames=SAMN04487818_11220 {ECO:0000313|EMBL:SES39058.1};
OS   Actinokineospora terrae.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Actinokineospora.
OX   NCBI_TaxID=155974 {ECO:0000313|EMBL:SES39058.1, ECO:0000313|Proteomes:UP000199051};
RN   [1] {ECO:0000313|EMBL:SES39058.1, ECO:0000313|Proteomes:UP000199051}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44260 {ECO:0000313|EMBL:SES39058.1,
RC   ECO:0000313|Proteomes:UP000199051};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FOGI01000012; SES39058.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1H9WYM5; -.
DR   STRING; 155974.SAMN04487818_11220; -.
DR   Proteomes; UP000199051; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   Gene3D; 3.40.50.1460; -; 1.
DR   InterPro; IPR029030; Caspase-like_dom_sf.
DR   InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR   InterPro; IPR011600; Pept_C14_caspase.
DR   PANTHER; PTHR22576:SF37; MALT1 PARACASPASE HOMOLOG; 1.
DR   PANTHER; PTHR22576; MUCOSA ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1/PARACASPASE; 1.
DR   Pfam; PF00656; Peptidase_C14; 1.
DR   SUPFAM; SSF52129; Caspase-like; 1.
DR   PROSITE; PS00018; EF_HAND_1; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199051};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        510..529
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        549..575
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        582..605
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        611..631
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        636..657
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        663..683
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        695..712
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        762..781
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          2..240
FT                   /note="Peptidase C14 caspase"
FT                   /evidence="ECO:0000259|Pfam:PF00656"
FT   REGION          313..502
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        319..338
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        347..361
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        366..412
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        424..452
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        466..480
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   792 AA;  83288 MW;  7EB9DA0E0A18B960 CRC64;
     MRRALIVASD AYGDLGLREL RAPKHDAAQL AAVLGDPEIG GFSVRTLHNA AVAETNEAIE
     DFFADRAPDE LLLLYFSGHG VKDETGDLYF ATAGTKLNRL AATAVAADFV RQRMNRTRAR
     RVVLLLDCCY AGAFGRGMVA RAGTAVALEE QFQGRGRAVI TASSAVEYAF EGQEVTDSAT
     GGPSVFTSAL VEGLRSGDAD RDQDGLVGLD ELYEYVYDRV RASTSNQTPG KWVFDLQGDL
     YIARRGRPVT VPSELPLELR EAISHPNRLV RVGAVDDLTR LLTGGHEGLA LAARLALEAL
     SDDDSRSVAA AATSTLAANR PPLPPPVRPE PARPDPVASV PSPAAQSEPD HPQPTRPGAH
     PQSTKPEPAQ PRSTQPEPDH PQSTRPGYAR PQSTQSGLTQ PQSAQSGFAR PQSGQPDAAP
     PPATQPSAAQ SKSTQPESTQ LESAQPQPAR SELGTPAQPE PDRPGPARSK QGRQRRGLAE
     IVRLKLAPPE HASDTPSPIT QSRETPRTLL VWRAVSAVLA IAAAVTLAAT PGDVALQTTY
     GSFVRGPVLV PASTSVLVPL VGWLLIAALV GLVVVHRGRR AIALGAAFGA IAIMAAFATR
     LAAIGVMGTP VRFYCLGLLG AFLAVVIANA VRRRGWLWEV ITGAGALTVA TVALAFPRYR
     DDTGTVVLIG LAVLVGAAVT HLVRTARAGR PVARDITFHA LVIAIACVGL ALDDVDMTIR
     LTVAALSLAA QPLFTDRGSL LPARAGLVAT LVVMVPPDVE DITQTLVLTS AAVIAAVVAM
     WPEPGKTRAR AV
//