ID   A0A1I0DD61_9CLOT        Unreviewed;       644 AA.
AC   A0A1I0DD61;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=MutS2 family protein {ECO:0000313|EMBL:SET30266.1};
GN   ORFNames=SAMN05660297_01992 {ECO:0000313|EMBL:SET30266.1};
OS   Natronincola peptidivorans.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Natronincola.
OX   NCBI_TaxID=426128 {ECO:0000313|EMBL:SET30266.1, ECO:0000313|Proteomes:UP000199568};
RN   [1] {ECO:0000313|EMBL:SET30266.1, ECO:0000313|Proteomes:UP000199568}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 18979 {ECO:0000313|EMBL:SET30266.1,
RC   ECO:0000313|Proteomes:UP000199568};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FOHU01000007; SET30266.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I0DD61; -.
DR   STRING; 426128.SAMN05660297_01992; -.
DR   OrthoDB; 9808166at2; -.
DR   Proteomes; UP000199568; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0004519; F:endonuclease activity; IEA:InterPro.
DR   GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR   GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR   GO; GO:0045910; P:negative regulation of DNA recombination; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR   InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR   InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR   InterPro; IPR005747; MutS2.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR48378; DNA MISMATCH REPAIR PROTEINS MUTS FAMILY DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR   PANTHER; PTHR48378:SF2; SMR DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00488; MutS_V; 1.
DR   PIRSF; PIRSF005814; MutS_YshD; 2.
DR   SMART; SM00534; MUTSac; 1.
DR   SMART; SM00533; MUTSd; 1.
DR   SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199568}.
FT   DOMAIN          405..421
FT                   /note="DNA mismatch repair proteins mutS family"
FT                   /evidence="ECO:0000259|PROSITE:PS00486"
FT   REGION          530..549
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   644 AA;  72451 MW;  DAACE586BD6AFC0C CRC64;
     MNKNPEEILE FHKIIETLGS YTLSDMGRKL VERLQPSIDI EVIEQWMLET TEAKKIVEKS
     ASIPLHSLQG IEGILEKLGK NNIFQPKELE SILELLMAGK RVKKFMMDKS SIAPLVSSYA
     LSIYEIKDIT EEIDRCIRNG RVDDRASTTL AKTRKKIIIL EERLKSKLES ILKSPQYAQY
     LQENLISMRN GRYVIPVKRE YRKSIDGEVL DSSSTGSTVF VEPKEVKKYY NELSLLKIEE
     EQEEYKILSY LTSMVESYER EIRINVETLA NYDFLFAKGK YSCSIKGNSI NLNQEGYIHI
     ESARHPLLGP SAVPLDFMVG KGYKALVITG PNTGGKTVTI KTIGLLTLMA QSGLHVPAKE
     ESQLAVFDNI LVDIGDGQSI QQSLSTFSSH IENIITIVEE ANERSLVIMD ELGAGTDPAE
     GTGLAAAILE TVYNKGATIL ATTHYSEIKS FAENHKGFKN GCMEFDIHSL KPLYKLHIGE
     SGESNAFLIA LRLGLNKGII ERAHEITYGY PKEYDGRIFE KNVVKVATSP VLKPPTNPKK
     KNPPKKAENN QRFKLGDCVY VSSLDATGIV YEEENSKGEV GVMVKKKKLK VNKKRLTLHI
     DGRHLYPEDY DLDIVFESKD NRKKKKLIGR KLIKGVAIEY TDES
//