ID A0A1I0EWQ9_9BACT Unreviewed; 322 AA.
AC A0A1I0EWQ9;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=D-3-phosphoglycerate dehydrogenase {ECO:0000313|EMBL:SET49106.1};
GN ORFNames=SAMN04487998_2002 {ECO:0000313|EMBL:SET49106.1};
OS Hymenobacter actinosclerus.
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Hymenobacteraceae;
OC Hymenobacter.
OX NCBI_TaxID=82805 {ECO:0000313|EMBL:SET49106.1, ECO:0000313|Proteomes:UP000198697};
RN [1] {ECO:0000313|Proteomes:UP000198697}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15310 {ECO:0000313|Proteomes:UP000198697};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the D-isomer specific 2-hydroxyacid
CC dehydrogenase family. {ECO:0000256|ARBA:ARBA00005854,
CC ECO:0000256|RuleBase:RU003719}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FOHS01000002; SET49106.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I0EWQ9; -.
DR STRING; 82805.SAMN04487998_2002; -.
DR OrthoDB; 1522997at2; -.
DR Proteomes; UP000198697; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR006139; D-isomer_2_OHA_DH_cat_dom.
DR InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR42789; D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G10090); 1.
DR PANTHER; PTHR42789:SF1; D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G10090); 1.
DR Pfam; PF00389; 2-Hacid_dh; 1.
DR Pfam; PF02826; 2-Hacid_dh_C; 1.
DR SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003719};
KW Reference proteome {ECO:0000313|Proteomes:UP000198697}.
FT DOMAIN 5..311
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase
FT catalytic"
FT /evidence="ECO:0000259|Pfam:PF00389"
FT DOMAIN 108..289
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02826"
SQ SEQUENCE 322 AA; 34863 MW; 460A82D74DF728A1 CRC64;
MSLCLVIDEM HPSLPEYLEP LGLTLHYRPD LTAAEVPAAL AAHPYEGLVV RSKLRITREL
LAYGPHLRYV CRAGAGVDNI DEAALAEAGV TLLNAPEGNR DAVGEYAVGL LLALFRHLPR
ADAEVRAGHW RREANRGEEI GGKTIGLLGY GHMGRAFARR LSAFGCTVLA HDHDPACPPD
DYATLVPLAE LRARAEVLSL HIPYAKANHH FVNEDFLAGF PNAIWLLNTA RGEVLDHAAL
VSGLRTGQIR GAALDVLENE KLTGLTPEQQ ARFDYLRTAA NVVLSPHIGG WTFQSYERIN
AVLARKLAAF LGVGEAGEQG VG
//
