ID   A0A1I0F315_9BACI        Unreviewed;       470 AA.
AC   A0A1I0F315;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   SubName: Full=Alanine or glycine:cation symporter, AGCS family {ECO:0000313|EMBL:SET52044.1};
GN   ORFNames=SAMN05216389_11388 {ECO:0000313|EMBL:SET52044.1};
OS   Oceanobacillus limi.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Oceanobacillus.
OX   NCBI_TaxID=930131 {ECO:0000313|EMBL:SET52044.1, ECO:0000313|Proteomes:UP000198618};
RN   [1] {ECO:0000313|EMBL:SET52044.1, ECO:0000313|Proteomes:UP000198618}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IBRC-M 10780 {ECO:0000313|EMBL:SET52044.1,
RC   ECO:0000313|Proteomes:UP000198618};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363064};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU363064}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the alanine or glycine:cation symporter (AGCS)
CC       (TC 2.A.25) family. {ECO:0000256|ARBA:ARBA00009261,
CC       ECO:0000256|RuleBase:RU363064}.
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DR   EMBL; FOHE01000013; SET52044.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I0F315; -.
DR   STRING; 930131.SAMN05216389_11388; -.
DR   OrthoDB; 9804874at2; -.
DR   Proteomes; UP000198618; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005283; F:amino acid:sodium symporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR   InterPro; IPR001463; Na/Ala_symport.
DR   NCBIfam; TIGR00835; agcS; 1.
DR   PANTHER; PTHR30330; AGSS FAMILY TRANSPORTER, SODIUM-ALANINE; 1.
DR   PANTHER; PTHR30330:SF1; AMINO-ACID CARRIER PROTEIN ALST; 1.
DR   Pfam; PF01235; Na_Ala_symp; 1.
DR   PRINTS; PR00175; NAALASMPORT.
DR   PROSITE; PS00873; NA_ALANINE_SYMP; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|RuleBase:RU363064};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363064};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198618};
KW   Symport {ECO:0000256|RuleBase:RU363064};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU363064};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU363064};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363064}.
FT   TRANSMEM        15..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        98..122
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        146..163
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        183..202
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        211..232
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        238..261
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        302..325
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        345..368
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        380..398
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        404..423
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
SQ   SEQUENCE   470 AA;  51188 MW;  F3641AFE1BC7EAC1 CRC64;
     MNLLESIIGE INNVLWSYVL IIILIGLGLW FTIRTNFVQF RNLPDMFRTL FDKRTVIATG
     KKGTSSFQAF AISAASRVGT GNLAGVASAV ALGGPGAIFW MWIIALFGAA SGFVESTLAQ
     VYKVPEKNQY RGGPAYYMEK GLKNRTLGIV FAITITFTYG LVFNSVQSNT ISLAFSGEFE
     VNQYVMAAVL AVLTAIVIFG GIRTIANVTQ IIVPFMAIIY IVVAIIILIL NITAIPDMFS
     LIVSNAFGIQ EVAGGGFGAA IMMGIKRGLF SNEAGMGSAP NAAATAEVTH PAKQGFIQAL
     GVFFDTILIC TATGFVILSA GGYAGSDLDG IQLTQNAFAS HIGTWAEFFI AIAIFLFAYS
     SILGNYYYGE SNIGYIRQNT VSLFLYRLAV IAMVFFGAVA SFDFVWGLAD LTMAIMALIN
     LYAITKLYKI AHRVLMDYRE QRKAGKDPVF YRDVLDEDDG VEYWERKQDK
//