ID A0A1I0F8Z8_9FIRM Unreviewed; 548 AA.
AC A0A1I0F8Z8;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Na+/H+-dicarboxylate symporter {ECO:0000313|EMBL:SET54403.1};
GN ORFNames=SAMN04487771_10247 {ECO:0000313|EMBL:SET54403.1};
OS [Clostridium] aminophilum.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=1526 {ECO:0000313|EMBL:SET54403.1, ECO:0000313|Proteomes:UP000199820};
RN [1] {ECO:0000313|EMBL:SET54403.1, ECO:0000313|Proteomes:UP000199820}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KH1P1 {ECO:0000313|EMBL:SET54403.1,
RC ECO:0000313|Proteomes:UP000199820};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FOIL01000024; SET54403.1; -; Genomic_DNA.
DR RefSeq; WP_074649584.1; NZ_FOIL01000024.1.
DR AlphaFoldDB; A0A1I0F8Z8; -.
DR STRING; 1526.SAMN02910262_02498; -.
DR eggNOG; COG1301; Bacteria.
DR OrthoDB; 9768885at2; -.
DR Proteomes; UP000199820; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015293; F:symporter activity; IEA:InterPro.
DR Gene3D; 1.10.3860.10; Sodium:dicarboxylate symporter; 1.
DR InterPro; IPR001991; Na-dicarboxylate_symporter.
DR InterPro; IPR036458; Na:dicarbo_symporter_sf.
DR PANTHER; PTHR42865; PROTON/GLUTAMATE-ASPARTATE SYMPORTER; 1.
DR PANTHER; PTHR42865:SF7; PROTON_GLUTAMATE-ASPARTATE SYMPORTER; 1.
DR Pfam; PF00375; SDF; 1.
DR PRINTS; PR00173; EDTRNSPORT.
DR SUPFAM; SSF118215; Proton glutamate symport protein; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000199820};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 137..154
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 174..198
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 210..233
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 287..305
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 317..338
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 358..381
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 461..480
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 486..512
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 548 AA; 59599 MW; 1B2A153BE3D1890C CRC64;
MNKKVLKADR DAIANGVNFI QESLKARDIS KRKIAQTLLT SEEVLAKILE SAPAESDIVI
EIKGHFGNLA IQIKSACEVF AVSDIYENLR IDEFDEDAGD VIRKLYDKLF ADTLSIRNSR
GKTTVTFPVK KSPYSSLVYT IAALVLGILT GFLIHKLFPA AVGKNISTII ITPIYTMFIN
FLKMIVAPLV FFSVAYSIAD FRDLKALGRI AFEMVIFYLM TSVIAIFVGY FTYQLFPIGN
TDLAMAVSEE TAESTLQKAE SVTISIKDTL VGIIPSDIIT PFQKSDMLQL IFMAVIFGIA
AASLAGKMPE FKRMLGIFNA VFSKITSVIV KLIPIVVFCS MAKMMIAMDF GTLLNVFVWT
PVVYFGDILM IGMYIILLAV FAGLAPHKFL KKYFPAMVSA FTCASSNAAL PTSIERCDKM
GISPKIYSFS LPLGATINMD GSCISLLISA LFCAKIFQIP VTPSVLLSLF ISIMVLSVGS
PGVPGGNLVC IALLIPQIGV PAEAISLIMG LYPLVGMMQT CTNVTGDAVV STIVAKREGL
LDTKKFNS
//
