ID A0A1I0G9S3_9CLOT Unreviewed; 577 AA.
AC A0A1I0G9S3;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=SAMN05660297_03109 {ECO:0000313|EMBL:SET67504.1};
OS Natronincola peptidivorans.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Natronincola.
OX NCBI_TaxID=426128 {ECO:0000313|EMBL:SET67504.1, ECO:0000313|Proteomes:UP000199568};
RN [1] {ECO:0000313|EMBL:SET67504.1, ECO:0000313|Proteomes:UP000199568}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 18979 {ECO:0000313|EMBL:SET67504.1,
RC ECO:0000313|Proteomes:UP000199568};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FOHU01000019; SET67504.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I0G9S3; -.
DR STRING; 426128.SAMN05660297_03109; -.
DR Proteomes; UP000199568; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0071555; P:cell wall organization; IEA:InterPro.
DR Gene3D; 1.10.1760.20; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR010559; Sig_transdc_His_kin_internal.
DR InterPro; IPR011620; Sig_transdc_His_kinase_LytS_TM.
DR PANTHER; PTHR34220; SENSOR HISTIDINE KINASE YPDA; 1.
DR PANTHER; PTHR34220:SF7; SENSOR HISTIDINE KINASE YPDA; 1.
DR Pfam; PF07694; 5TM-5TMR_LYT; 1.
DR Pfam; PF13185; GAF_2; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF06580; His_kinase; 1.
DR SMART; SM00065; GAF; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Kinase {ECO:0000313|EMBL:SET67504.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000199568};
KW Transferase {ECO:0000313|EMBL:SET67504.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 43..64
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 76..98
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 110..130
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 142..162
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 174..194
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 227..362
FT /note="GAF"
FT /evidence="ECO:0000259|SMART:SM00065"
SQ SEQUENCE 577 AA; 63988 MW; FDA9DA5F024AF8B8 CRC64;
MILIIGEMML SLLNKLGIII ILAVIISKIG IFRKLIIKKN ITFMDKIFLS IVFGAIGIMG
TYSSVPINGA LANTRIVGVM VGALLGGPMV GFMAGLIAGG HRFLIDIGGF TAVACGVATI
VEGLFGGYAH YYIRNKSPKW EWAFLLGVIS EFIQMIIILL IARPFGDALQ LVKIILFPMV
VVNSFGIAIF IGIIENIYTE YDRIAASQAE KTLKIANLTL PYLRQGLNYE VAQKVVGIIK
ESVDVAAVTI TNRHEILAHK GIGEDHHCQG FDLQTEATKE VIQTGQYKII NDKDSIKCIK
NDCTLKSAIV VPLKERDRVV GILKLYRTEE NSITSIDTEL ALGLAQLFST QIELSRVEHQ
NKLITEAELK SLQAQINPHF LFNAINTIVS FIQFDSGKAK QLLISLAELF RKSLSNNQDM
VDMDVELKHI ASYLEIEKAR FGDKLQVKYD IQKNVVCKLP PLILQPIVEN AVVHGILPKK
SGGSVTIRCR KNHEDILLEV IDDGIGMEAE ELKGLLNQQS DTNCIGLMNV NRRLINLYGE
EYKLQIKSTY NEGTSVLIKI PYVKGRYSSE VKEEIVA
//
