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Database: UniProt
Entry: A0A1I0GXW9_9CLOT
LinkDB: A0A1I0GXW9_9CLOT
Original site: A0A1I0GXW9_9CLOT 
ID   A0A1I0GXW9_9CLOT        Unreviewed;       290 AA.
AC   A0A1I0GXW9;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   SubName: Full=Small conductance mechanosensitive channel {ECO:0000313|EMBL:SET75336.1};
GN   ORFNames=SAMN05660297_03388 {ECO:0000313|EMBL:SET75336.1};
OS   Natronincola peptidivorans.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Natronincola.
OX   NCBI_TaxID=426128 {ECO:0000313|EMBL:SET75336.1, ECO:0000313|Proteomes:UP000199568};
RN   [1] {ECO:0000313|EMBL:SET75336.1, ECO:0000313|Proteomes:UP000199568}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 18979 {ECO:0000313|EMBL:SET75336.1,
RC   ECO:0000313|Proteomes:UP000199568};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the MscS (TC 1.A.23) family.
CC       {ECO:0000256|ARBA:ARBA00008017}.
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DR   EMBL; FOHU01000027; SET75336.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I0GXW9; -.
DR   STRING; 426128.SAMN05660297_03388; -.
DR   OrthoDB; 9809206at2; -.
DR   Proteomes; UP000199568; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008381; F:mechanosensitive monoatomic ion channel activity; IEA:InterPro.
DR   Gene3D; 1.10.287.1260; -; 1.
DR   Gene3D; 2.30.30.60; -; 1.
DR   Gene3D; 3.30.70.100; -; 1.
DR   InterPro; IPR010920; LSM_dom_sf.
DR   InterPro; IPR049142; MS_channel_1st.
DR   InterPro; IPR049278; MS_channel_C.
DR   InterPro; IPR023408; MscS_beta-dom_sf.
DR   InterPro; IPR006685; MscS_channel_2nd.
DR   InterPro; IPR011066; MscS_channel_C_sf.
DR   InterPro; IPR011014; MscS_channel_TM-2.
DR   InterPro; IPR045276; YbiO_bact.
DR   PANTHER; PTHR30460:SF0; MODERATE CONDUCTANCE MECHANOSENSITIVE CHANNEL YBIO; 1.
DR   PANTHER; PTHR30460; UNCHARACTERIZED; 1.
DR   Pfam; PF21088; MS_channel_1st; 1.
DR   Pfam; PF00924; MS_channel_2nd; 1.
DR   Pfam; PF21082; MS_channel_3rd; 1.
DR   SUPFAM; SSF82689; Mechanosensitive channel protein MscS (YggB), C-terminal domain; 1.
DR   SUPFAM; SSF82861; Mechanosensitive channel protein MscS (YggB), transmembrane region; 1.
DR   SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199568};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        28..46
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        82..99
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        105..125
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          82..122
FT                   /note="Mechanosensitive ion channel transmembrane helices
FT                   2/3"
FT                   /evidence="ECO:0000259|Pfam:PF21088"
FT   DOMAIN          123..185
FT                   /note="Mechanosensitive ion channel MscS"
FT                   /evidence="ECO:0000259|Pfam:PF00924"
FT   DOMAIN          197..278
FT                   /note="Mechanosensitive ion channel MscS C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF21082"
SQ   SEQUENCE   290 AA;  32483 MW;  6EE25E0836855212 CRC64;
     MGTFMNRIET SLQETMEFLR NPEQLTKILG LIINIILILF IAKISIKIIH SVSNRFFQSQ
     KSLKLKVDPA RMETMNGLIK SIVKYLIYFI AFTSIIKSFG VEVGALIATA GIGGLAFGFG
     AQNLVRDVIT GFFILFEDQF AVGDYVEIDG VGGIIEEMAL RVTKIRDFNG DLHILPNGEI
     KKVTNKSTGK MRAWVNMSIA YEEDIDKAIQ VLTEVSEKLK EENNNILEGP IVLGVTDLGD
     SDVVISVIAK TEPMEQWATE RLMRKSFKQA FDKEGIEIPY PRRVVINKDA
//
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