ID   A0A1I0I1N4_9FIRM        Unreviewed;      1570 AA.
AC   A0A1I0I1N4;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Uncharacterized Sugar-binding Domain {ECO:0000313|EMBL:SET89608.1};
DE   Flags: Fragment;
GN   ORFNames=SAMN04489758_1701 {ECO:0000313|EMBL:SET89608.1};
OS   Thomasclavelia cocleata.
OC   Bacteria; Bacillota; Erysipelotrichia; Erysipelotrichales;
OC   Coprobacillaceae; Thomasclavelia.
OX   NCBI_TaxID=69824 {ECO:0000313|EMBL:SET89608.1, ECO:0000313|Proteomes:UP000198558};
RN   [1] {ECO:0000313|Proteomes:UP000198558}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 1551 {ECO:0000313|Proteomes:UP000198558};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FOIN01000070; SET89608.1; -; Genomic_DNA.
DR   Proteomes; UP000198558; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProt.
DR   Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR   Gene3D; 1.20.1270.70; Designed single chain three-helix bundle; 2.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 4.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   Gene3D; 1.20.120.670; N-acetyl-b-d-glucoasminidase; 1.
DR   InterPro; IPR000421; FA58C.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR029018; Hex-like_dom2.
DR   InterPro; IPR007781; NAGLU.
DR   InterPro; IPR024732; NAGLU_C.
DR   InterPro; IPR024240; NAGLU_N.
DR   InterPro; IPR024733; NAGLU_tim-barrel.
DR   PANTHER; PTHR12872; ALPHA-N-ACETYLGLUCOSAMINIDASE; 1.
DR   PANTHER; PTHR12872:SF1; ALPHA-N-ACETYLGLUCOSAMINIDASE; 1.
DR   Pfam; PF00754; F5_F8_type_C; 4.
DR   Pfam; PF07554; FIVAR; 2.
DR   Pfam; PF05089; NAGLU; 1.
DR   Pfam; PF12972; NAGLU_C; 1.
DR   Pfam; PF12971; NAGLU_N; 1.
DR   SUPFAM; SSF49785; Galactose-binding domain-like; 4.
DR   PROSITE; PS50022; FA58C_3; 4.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198558};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..28
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           29..1570
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5011629196"
FT   DOMAIN          29..151
FT                   /note="F5/8 type C"
FT                   /evidence="ECO:0000259|PROSITE:PS50022"
FT   DOMAIN          175..318
FT                   /note="F5/8 type C"
FT                   /evidence="ECO:0000259|PROSITE:PS50022"
FT   DOMAIN          323..464
FT                   /note="F5/8 type C"
FT                   /evidence="ECO:0000259|PROSITE:PS50022"
FT   DOMAIN          1194..1348
FT                   /note="F5/8 type C"
FT                   /evidence="ECO:0000259|PROSITE:PS50022"
FT   NON_TER         1570
FT                   /evidence="ECO:0000313|EMBL:SET89608.1"
SQ   SEQUENCE   1570 AA;  179213 MW;  958847C2802DF067 CRC64;
     MNLKKKLKIS LILSLVLVLL FPTMTIFASE TKSRAARENI ALNKPVTSSK IENSNIPEYA
     VDGKENTFWA SVNPSELEVD LQGFYKISEI NLMAYFDVPA NAERYYDYEI YASMDQEKYD
     LVAKKSDTSW NTPQGDTYVF NDTFTAHYIK VKILKTHAEN QPNNNTGHIK ELRVYGELDP
     EYENPVIKSN VALNKTVTAS GQEGSSNPGK AVDNNVNSFW AVAGEGWLEV DLEGYFDVDE
     INVLPYYSDG RYYNYEVYVS VNGLDYIKAG EKKDNTPQNK DGDTYTFDTK TIRFVKVKML
     SNSANPSMHI NELRVYGIEN TEYKPPIEDI DTTSIAYQKP ARSYSNSASY PVSNINDGML
     STSWQALYYP AYIDIDLEGN YNINKIQVVP DFKDLQAYYQ YSIFTSIDGV TFDKVAKKDD
     DTVVTKEGNL FEINGKEARI VRVYLEYCSV GNTGSFAEVR VYGEESENPV IERADINISD
     FEDTEYVLPI TEDETINEVK GVLSRVIGEK YLDWFEFVLE ENSESDKDYY EISNHNGKIK
     IKGNEGLSLT TGLNYYLKYY CNVSITQQAR QVKMPANVVP VTETIRKETP YEVRYAYNYC
     THSYTMAFWG ETEWQNEMDW LALNGVNAIL DITGQEEVWR RFMGNLGYSL DEIKDWLVGP
     GYYGWQYMAN MENVNGPIPD NWFAQRTELA RMNQRKMRAL GMTPILQGYS GMVPNSITEK
     DSKAQVIPQG LWNGMQRPAM LKTNTETYKE YAKMFYQAQE EVYGKVSNYY ATDPFHEGGQ
     TGGIGRDIVG RKVLDEMKVY DDDAIWVIQS WSFQPALLSE ITTEEKQNNI LLLDLNASKS
     AKYSSTNEFA GSNWVYCMLE NYGGRSGVHG NLEKLTKIPS QVKDKTSHMV GMGIAPEGTN
     NNPVRFDLFF EMMWEENDVD LNEWITHYVE RRYGCENENA QKAWKLLLET VYRPATHADP
     PESIINVRPQ FNAKQSAPNG NMSKNYDFKR FEKALDYLMK DFEQLKGSEG YLYDVTDFLR
     QAVANSAERT YSEFTKAFND GNVELFKEKS QEFLKMVELQ DQVLNSNKNF MVGTWLNASK
     NASEGQDDFI KMIFQLNGKA LISTWAPYYC WGVYDYANRE YGGLTKDYYL QRWELWIQRL
     TDKIEGKNVS NYNEISIKES HQMAWQWARS EKDYSSEATG DTKELYKEFV NNYCLNNGSV
     DELQVDKMSI SISCDKPDYN GYPISNAIDG NAGSFWTTQT NIKGPYTVTF KFDQAETINS
     FSILPRNYNS NATGNGDILG IELWVSDDGN EYRKIAQGEY EQNGSERICN FEAVTTKYVK
     LVITKTLIWN NVATNASASA AEFSFYKPYA QLRSGIYTIE NNVIGNVYEN TTVKQFLAGF
     DISQNGKVIV TRNGNELTEN DVIEQDDIVE YYYKNEKVKT YQIDEFAQVS DFTKLNELIL
     ECEKLNQNDY TEESWNQFSE ILTLAVGVQV NPEASQEEID NAVKNLKEAY SNLVSVTVVS
     KTALQIAVEM AGNVTEEQLD KVVPAVVTEF NAALEEARTI LANDNATQEE VDASFARLSV
     AMHMLEFLKG
//