ID A0A1I0K117_9ACTN Unreviewed; 402 AA.
AC A0A1I0K117;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=imidazolonepropionase {ECO:0000256|ARBA:ARBA00012864};
DE EC=3.5.2.7 {ECO:0000256|ARBA:ARBA00012864};
GN ORFNames=SAMN05421811_106417 {ECO:0000313|EMBL:SEU16204.1};
OS Nonomuraea wenchangensis.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Streptosporangiaceae; Nonomuraea.
OX NCBI_TaxID=568860 {ECO:0000313|EMBL:SEU16204.1, ECO:0000313|Proteomes:UP000199361};
RN [1] {ECO:0000313|EMBL:SEU16204.1, ECO:0000313|Proteomes:UP000199361}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 4.5598 {ECO:0000313|EMBL:SEU16204.1,
RC ECO:0000313|Proteomes:UP000199361};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Amino-acid degradation. {ECO:0000256|ARBA:ARBA00005023}.
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DR EMBL; FOHX01000006; SEU16204.1; -; Genomic_DNA.
DR RefSeq; WP_020541796.1; NZ_FOHX01000006.1.
DR AlphaFoldDB; A0A1I0K117; -.
DR STRING; 568860.SAMN05421811_106417; -.
DR OrthoDB; 9776455at2; -.
DR Proteomes; UP000199361; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0050480; F:imidazolonepropionase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0019556; P:histidine catabolic process to glutamate and formamide; IEA:InterPro.
DR Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR Gene3D; 2.30.40.10; Urease, subunit C, domain 1; 1.
DR InterPro; IPR006680; Amidohydro-rel.
DR InterPro; IPR005920; HutI.
DR InterPro; IPR011059; Metal-dep_hydrolase_composite.
DR InterPro; IPR032466; Metal_Hydrolase.
DR NCBIfam; TIGR01224; hutI; 1.
DR PANTHER; PTHR42752; IMIDAZOLONEPROPIONASE; 1.
DR PANTHER; PTHR42752:SF1; IMIDAZOLONEPROPIONASE-RELATED; 1.
DR Pfam; PF01979; Amidohydro_1; 1.
DR SUPFAM; SSF51338; Composite domain of metallo-dependent hydrolases; 1.
DR SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
PE 4: Predicted;
KW Histidine metabolism {ECO:0000256|ARBA:ARBA00022808};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000199361};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 242..398
FT /note="Amidohydrolase-related"
FT /evidence="ECO:0000259|Pfam:PF01979"
SQ SEQUENCE 402 AA; 42643 MW; A4EBE03BE8759165 CRC64;
MTVRLLTNIG RLWTGNEVLS NAAILVHNDR IAWVGRAPDL PQSVPGVVDD IVDVDHVENL
GGALVTPGLI DAHTHPVYAG NRYAELAIRT GGSSAASITA AGGGVGSTVT VTRGTDPWTL
CNGVRERLRG WLLSGTTTVE AKTGYHLTRD GELADVRLLR ELEKEPMMPR VHVTFLAAHV
VPPEYFGRQR EYVEAVGAWC ADAAAAGADS VDVYCDEGHF TTEESRWVLA SGRNVGLLPR
IHAGLFARRG AVQLAAELGC ASADGLHHMS DEDIAIMSRY GVPAVVCPAT ALQRGHLPPV
RQMIKHGVQI ALGSDHNPGY CGITSMSLVI AMAVSAFGMS VNDALRAATL GGATVLGAPD
RGVLAPGRLA DIVQWDADHE GAFAWSFGLK PRRVWRGGTP VQ
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