ID A0A1I0KHL2_9ACTN Unreviewed; 348 AA.
AC A0A1I0KHL2;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=LacI family transcriptional regulator {ECO:0000313|EMBL:SEU24019.1};
GN ORFNames=SAMN05421811_10825 {ECO:0000313|EMBL:SEU24019.1};
OS Nonomuraea wenchangensis.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Streptosporangiaceae; Nonomuraea.
OX NCBI_TaxID=568860 {ECO:0000313|EMBL:SEU24019.1, ECO:0000313|Proteomes:UP000199361};
RN [1] {ECO:0000313|EMBL:SEU24019.1, ECO:0000313|Proteomes:UP000199361}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 4.5598 {ECO:0000313|EMBL:SEU24019.1,
RC ECO:0000313|Proteomes:UP000199361};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FOHX01000008; SEU24019.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I0KHL2; -.
DR STRING; 568860.SAMN05421811_10825; -.
DR OrthoDB; 9785139at2; -.
DR Proteomes; UP000199361; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF152; HTH-TYPE TRANSCRIPTIONAL REGULATOR EBGR-RELATED; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000199361};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 3..57
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 348 AA; 36728 MW; 49559E17F65D7C7F CRC64;
MRIGLKEVAA EAGVSRSTAS RALSGSPLIS AETRAAVEQA AARLNYQPNR LAGALRSKQS
HLVGLVLNNL INASFHTIAE VVQRRAADEG YQVMLGITDA DPAREKEFLR TLAAHGVDGL
IVIGTGKNGA TTNALLAEGT GVVNVIRRPA DSAAPSVLAA DREGAHAATS HLLDLGHERI
GFIGGELTAD SGRERFAGYE QALRERGLAV DESLVERGPF APGFGTEAIT RLLRRAPRMT
ALFAANHEAV FGILPTLAST GVSVPGDLSL VCHEDISWLR YWSPAITVVD NGAAELGELA
MNLLLQQMKH GDGGRDGAQE ARNGRAYRVG AQLVIRDSTA PPATRRDG
//
