ID   A0A1I0KUT5_9BACL        Unreviewed;       466 AA.
AC   A0A1I0KUT5;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Putative MFS transporter, AGZA family, xanthine/uracil permease {ECO:0000313|EMBL:SEU28925.1};
GN   ORFNames=SAMN03159358_4724 {ECO:0000313|EMBL:SEU28925.1};
OS   Paenibacillus sp. NFR01.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX   NCBI_TaxID=1566279 {ECO:0000313|EMBL:SEU28925.1, ECO:0000313|Proteomes:UP000198735};
RN   [1] {ECO:0000313|EMBL:SEU28925.1, ECO:0000313|Proteomes:UP000198735}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NFR01 {ECO:0000313|EMBL:SEU28925.1,
RC   ECO:0000313|Proteomes:UP000198735};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|PIRNR:PIRNR005353};
CC       Multi-pass membrane protein {ECO:0000256|PIRNR:PIRNR005353}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC       2.A.40) family. Azg-like subfamily. {ECO:0000256|ARBA:ARBA00005697,
CC       ECO:0000256|PIRNR:PIRNR005353}.
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DR   EMBL; FOIK01000008; SEU28925.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I0KUT5; -.
DR   STRING; 1566279.SAMN03159358_4724; -.
DR   OrthoDB; 9808458at2; -.
DR   Proteomes; UP000198735; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:1904823; P:purine nucleobase transmembrane transport; IEA:UniProt.
DR   InterPro; IPR045018; Azg-like.
DR   InterPro; IPR026033; Azg-like_bact_archaea.
DR   InterPro; IPR006043; NCS2.
DR   PANTHER; PTHR43337; XANTHINE/URACIL PERMEASE C887.17-RELATED; 1.
DR   PANTHER; PTHR43337:SF1; XANTHINE_URACIL PERMEASE C887.17-RELATED; 1.
DR   Pfam; PF00860; Xan_ur_permease; 1.
DR   PIRSF; PIRSF005353; PbuG; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|PIRNR:PIRNR005353};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR005353};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198735};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|PIRNR:PIRNR005353};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|PIRNR:PIRNR005353};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR005353}.
FT   TRANSMEM        12..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        47..70
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        101..125
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        137..154
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        193..211
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        216..234
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        263..289
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        310..333
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        353..385
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        397..414
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        420..437
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        444..462
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   466 AA;  49405 MW;  A7D9FD12DBDAF6C6 CRC64;
     MNRFFKLKEN GTTVRTEIMA GLTTFMAMAY ILSVNPGTLT AFGRIDMGWY SVFLATALAA
     GIFTIAMGLF INFPVALAPG MGLNAYFASV VLSSATSENH FTWQMGLTAV FISGLIFILL
     TVTQIRQILL TAIPDSLKHA ITVGIGLFIT IIGLKNSGLM TIGVEAGNDI AANKFTDVLS
     FETVIHMGSL DNTSVQLAII GLLLIGILMV LRVKGAILFG ILGTTVVAIL MGAVDFSSLN
     NPQTPWVPDF TQLNFWDFDW DGIMHTGIVS AIATFTFVEL FDTFGTLVGT AERAGIMKNA
     EEGKKRVGKA MFVDAVAVAG GAVLGTSTTT AYVESAAGVA EGGRTGLTAV TTGVCFLLAL
     FLAPVAALIP GSATAAALII VGVLMAQSIR EIDFQDMVLA IPAFLTFAIM PFTYNIANGI
     SFGIVTYVIL AGVANLAGKK KYNIHWMMWV LAVLIILRYV LIGSQG
//