ID A0A1I0M684_9FIRM Unreviewed; 447 AA.
AC A0A1I0M684;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Radical SAM superfamily enzyme YgiQ, UPF0313 family {ECO:0000313|EMBL:SEV83789.1};
GN ORFNames=SAMN05421659_101227 {ECO:0000313|EMBL:SEV83789.1};
OS [Clostridium] fimetarium.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=99656 {ECO:0000313|EMBL:SEV83789.1, ECO:0000313|Proteomes:UP000199701};
RN [1] {ECO:0000313|EMBL:SEV83789.1, ECO:0000313|Proteomes:UP000199701}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 9179 {ECO:0000313|EMBL:SEV83789.1,
RC ECO:0000313|Proteomes:UP000199701};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
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DR EMBL; FOJI01000001; SEV83789.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I0M684; -.
DR STRING; 99656.SAMN05421659_101227; -.
DR OrthoDB; 9801659at2; -.
DR Proteomes; UP000199701; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR Gene3D; 3.80.30.20; tm_1862 like domain; 1.
DR InterPro; IPR006158; Cobalamin-bd.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR034466; Methyltransferase_Class_B.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR023404; rSAM_horseshoe.
DR PANTHER; PTHR43409; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE-RELATED; 1.
DR PANTHER; PTHR43409:SF12; BLL1977 PROTEIN; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDG01082; B12-binding_domain_containing; 1.
DR SFLD; SFLDG01123; methyltransferase_(Class_B); 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51332; B12_BINDING; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Coiled coil {ECO:0000256|SAM:Coils}; Iron {ECO:0000256|ARBA:ARBA00022485};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00022485};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000199701}.
FT DOMAIN 7..131
FT /note="B12-binding"
FT /evidence="ECO:0000259|PROSITE:PS51332"
FT DOMAIN 155..366
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
FT COILED 269..296
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 447 AA; 51592 MW; EBDB15AECAD3D648 CRC64;
MIIKLIQPKM IMRPMDTQLK TRMSPSLGLL TIANIFHNEH TVIIENENIE DINFNDVVDI
VGITVTVDVM VRATEIAEIY KSKGIPVVAG GIHITAFSEQ VKKYFDVISI GLAEKTWPDI
IRDLQDKKLK KIYSCNSEIK GCEIVSPGYH LIDKKKYLFC NVISTSRGCP FQCDFCYNSS
EAYKKLYINR PIIDVIADIK TIGKRHVMFI DDNFIGNPKW TLEFVRSIRP MHLKWNAAVS
ANMVDMLDLL DEMALSGCES LFIGFESLNE NAIKNIHKGQ NNIRKYEKLV EEIHNRGIMI
NASFVFGLDA DDSTTFQTTL DWIVKNKIET VTSHILTPYP GTIVYDEFVT NDRITDFDFS
KYNTANVVFK PPNMTAEELY NGYLWIYKQV YSIKNILKRV PKTHRQRVPY FLFNFVYRKF
GKVTDNICKL ITYERVGKIA EKLSYRL
//
