ID A0A1I0MNQ5_9EURY Unreviewed; 545 AA.
AC A0A1I0MNQ5;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=SAMN04487945_0240 {ECO:0000313|EMBL:SEV90104.1};
OS Halobacterium jilantaiense.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Halobacteriaceae; Halobacterium.
OX NCBI_TaxID=355548 {ECO:0000313|EMBL:SEV90104.1, ECO:0000313|Proteomes:UP000198518};
RN [1] {ECO:0000313|EMBL:SEV90104.1, ECO:0000313|Proteomes:UP000198518}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 1.5337 {ECO:0000313|EMBL:SEV90104.1,
RC ECO:0000313|Proteomes:UP000198518};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FOJA01000001; SEV90104.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I0MNQ5; -.
DR STRING; 355548.SAMN04487945_0240; -.
DR Proteomes; UP000198518; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0004673; F:protein histidine kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR CDD; cd06225; HAMP; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR033479; dCache_1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR44936:SF9; SENSOR HISTIDINE KINASE GLNK; 1.
DR PANTHER; PTHR44936; SENSOR PROTEIN CREC; 1.
DR Pfam; PF02743; dCache_1; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:SEV90104.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000198518};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 270..322
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 337..542
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 545 AA; 58478 MW; EA6E7463B1E72948 CRC64;
MRSRRIFVVL LVTSAVVLSG ATWAGFQAYQ DAVMDEHHAD VERSGDLVRV GLDARLAAQR
QTVELWSGVP AVADHGTDGQ RAALDRLVGD TLFSGASVVA ANGTMTALVS DLSPADRDAV
VGTNFGDRTY VQRAMAGETY VSDPVAAQTG NTVVTVSAPV RHDGEVVATL NAALHLSETE
FFDAATGSLD AETGVTVTAS DGTVIYERAP SPNTSLTTAR VSLSEVPWRV TVSESRASVQ
PAIRRLSLLQ AGSVAAVLAV VAGFGWWNYR RNVSQFEALR DGFEALQNGE YGTHIDVGGP
DEWERIGRGF DEMSDTVRRS VDESRERARQ LQVLDRVLRH TLRNELNVVR GRAELLADAD
DPGVAGHAAH IVERCDDLLE TAEKERVINQ VLDTDTSAGP VDIPHAVERA VETARDDYPD
AAIALDAPDH ARAVTVPQFG VAVRELVENG IRHADRGPAQ VAVDVTADED VVRVRVTDHG
PGIPEMERRV LSGEDAIDEL HHSQGLGLWL VHWTVAHSGG DLSFADNDPR GSVVTITLPV
PPEGP
//
